The Cohort Study on Intake of Alcohol and Lung Cancer Risk in the Yunnan Tin Corporation(YTC)Miners

The relationship between alcohol intake and lung cancer risk was studied among the Yunnan Tin Corporation(YTC)miners.On the basis of the reproducibility and validity of Food Frequency Questionnaire(FFQ),the alcohol intake was calculated and the correlation between the different intake of alcohol and relative risk of lung cancer in population with lung cancer athigh risk was analyzed by means of Chi-square,Cox regression model.The results show that there are significantly different incidence of lung cancer among subjects consuming different levels of alcohol(P<0.01);"J shape" correlation was found,i.e.the incidences of lung cancer of non drinkers and more than medium drinkers(intake of alcohol ≥50 g/d)is significantly higher incidence than that of light-drinkers(intake of alcohol 0～50g/d);light-drinkers are significantly negative correlation with lung cancer risk(RR<1,P<0.01);heavy-drinkers(intake of alcohol≥100g/d)are significantly positive correlation with lung cancer risk(RR>1,P<0.01);after adjusting confounders such as age,occupational history and smoke,medium and heavy-drinkers are significantly positive correlation with lung cancer risk(RR>1,P<0.01).It can be considered that alcohol is a risk factor to develop lung cancer at YTC and may have synergic effects with occupational risk factors.