Effect of Zinc Deficiency on the Concentrations of Acetylcholine and Serotonin in Blood and Brain of Rats

ObjectiveThe effects of zinc deficiency on the concentrations of acety lcholine(ACh)and serotonin(5-HT)in blood and brain of rats were studyed in present experiment.MethodsAbout 85g Wistar rats were alloted to zinc dificiency group (ZD),fed zinc deficient diet;pair-fed group(PF),fed adequate zinc diet;and zinc deficiency and zinc supplementation group (ZS),fed adequate zinc diet after fed zinc deficiency diet for 21 days.The duration was 35 days.ResultsZinc denciency resulted in the significant increase of blood.Achand 5-HT,and brain 5HT.ConclusionThe results suggested that zinc might change the metabolism of ACh and 5-HT in blood and brain.