Effect of SOD Inducer on the Free Radical Content of the Bone、Liver and Kidney of the Chronic Fluorosis Rats

Objective In order to study decply on the fluorosis mochanism,we observed the free radical bone、liver and kidney and the anti-oxygen system of the erythrocyte in the chronic fluorosis rats with SOD inducer.Methods The SOD、GSH-Px activities of erythrocyte and contents of plasma MDA were detected with biochemistry.The free radical contents of bone、liver and kidney were detected with ESR technolgy.Result The activities of SOD、GSH-Px of erythrocyte and the content of the plasma MDA,and the free radical contents of bone、liver and kidney in the fluorosis animals with SOD inducer were no changes as compared with the control animals(P>0.05),whereas were markedly decreased as compared with the fluorosis rats(P<0.05).Conclusion The results indicated that the SOD inducer may recover the activities of free radical scavenging enzymes(SOD、GSH-Px)and decreased the free radical contents of bone、liver and kidney.