Study on Safety and Immunity of Influenza Vaccine for Children

Objective To study safety and immunogenicity of the influenza vaccine for children(Pastedur Merieux Biological Products Co.,Ltd).Methods Sixty-nine children aged below three years were selected randomly living in suburb of Tianjin city and vaccinating the influenza vaccine.Results The local-reaction rate was 2.9% and the systemic-reaction rate was 7.2%.The antibody positive rate of the influenza type H1N1,type H3N2 and type B was 83.7%,77.6% and 85.7% respectively after vaccination.The rate of antibody titer for three type≥1:40,were 95;9%,95.9%,38.8% respectively.Conclusion The vaccine was safe and the immunity of the influenza vaccine was good except type B.