Study of Hepatitic Virus Infection in Patients on Hemodialysis

ObjectiveTo study the infect ion of hepatitis Bvirus(HBV)、hepatitis Cvirus(HCV)and hepatitis G virus on hemodialysis.MethodsHBsAg,HBsAb,HBeAg,HBeAb,HBcAb,and anti-HCV and anti-HGV were measured in 1 478 patients on hemdialysis over 3 mothes by Enzyme Immunassay.HBV-DNA was determined by polymerase chain reaction (PCR).100positive patients of them for anti-HCV and anti-HGV were determined for HCV-RNA and HGV-RNA by rev erse transcription+nested poly merase chain reaction(RT-PCR).ResultsIn 1 478 patients,the infection rate of HBV was 43.9% (649/1 478),7.9% (117/1 478)patients were positive for HBV-DNA,the infection rate of HCV was 42.6% (630/1 478);the infection rate of HGVwas 46.4% (685/1 478);In 100 positive patients of anti-HCV and anti-HGV, 73% and 77% patients were positive for HCV-RNA and HGV-RNA.ConclusionHepatitis virus infection exists in patients on hemodialysis.It was very important to study risk factors that were related to hepatitis virus.