Study of Long-term Exposure to Lower Concentration of Carbon Disulfide on Cardiovascular System of Workers

Objective To evaluate viscose rayon workers for cardiovascular manifestations resulting from exposure to carbon disulfide at the level of the threshold limit value of 10mg/m³ long-term.Methods In a cross-sectional study we investigated 367 workers occupationally exposed to CS₂ and a control group(n=125).Results there was a singificant increase in the serum levels of total cholesterol and ApoB(P<0.05).These differences could also be confirmed statisically after multiple stepwise regression analysis.No differences were noted as to concentration of Hdl-ch、Ldl-ch、ApoA-I and so on among three groups.Conclusion The findings may indicate that exposure to CS₂ can increase the levels of total cholesterol and ApoB in the serum,namely,low-level exposure to CS₂ long-term could increase the risk of workes developing CS₂-indued cardiovascular abnormalities.