Studies on side effect and immunolical effect of CTN-IV Stain

Objective To observe the immunological effect and side effect of CTN-1v strain.Methods Detection of neutralizing antibody and observation of side effect is carried in 20 volunteers who are vaccinated by CTN-1v vaccine.Results Rates of side effect are 35%(7/20),the rates of positive antibody are 100%(20/20),and the level of neutralizing antibody was 13.08 IU/ml(5.83-22.16 IU/ml).Conclusion CTN-1v strain is characterized by side effect slightly and good immunolonicity,large production of antibody.