Objective To find out the relations among lead, magnesium and ADHD and provide exoteric basis for further individual prevention and cure step.
Methods Sixty ADHD cases were diagnosed by employing ADHD Behavior Screen with DSM-IV.The control group was confirmed according to 11 matched case-control study design, then lead and magnesium in childrens distal blood and hair were collected and analyzed by atom-absorbed spectr ophotometer(graphite stove and blaze method).Data was analyzed with SAS6.12 statistics softw are.
Results In ADHD group, the contents of blood lead were hig her(P < 0.001), the contents of blood mag nesium were lower(P < 0.001), the contents of hair mag nesium were lower(P < 0.05)than control group.There was inter actions between lead and magnesium in blood; between magnesium in blood and magnesium in hair.
Conclusion Lead exposure and magnesium deficithelped to ADHDs occurrence.The inter acting analysis of lead and magnesium in blood showed that they antagonized each other in ADHDs etiology.
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