Objective To investigate the effect of exper imental reducing fat on leptin resistance and insulin resistance in adolecent g irl students with simple obesity.
Methods Simple obesity students accepted the reducing weight therapy composed of the aerobicex ercise, reasonable diet, behavior modification forten month.Then the changes of blood leptin and insulin were examined pre-and post-treatment.
Results The leptin and insulin level were significantly higher in obese subjects than that in normal subjects, and the leptin and insulin level were decreased obviously afterexper imental reducing fat.
Conclusion There are leptin resistance and insulin resistance in adolecent girl students with simple obesity.The experimental reducing fat can decrease the leptin and insulin level, so it plays an important role in adjusting metabolism disorder.
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