Effects of measles vaccine on unmarried women of child-bearing age

  Objective   To evaluate the immune status and the effect of vaccination on unmarried women of child-bearing age and to decrease newborn baby's incidence of measles.

  Methods   474 women were randomly recruited from 15 districts.Their serum samples were collected and IgG antibody of measles was tested with enzyme-linked immunosorbent assay (ELISA)before and after the vaccination.

  Results   Among the 474 women,positive rate of IgG was 82.28%.The geometric mean titer(GMT)of measles antibody was 1:478.62;percentage of low antibody level was 94.39% before the vaccination.GMT was 1:1 368.38 after the vaccination,significantly higher than that of the previous value(P<0.01).Similarly,the positive rate of IgG antibody in different age groups rose significantly after the vaccination.

  Conclusion   In order to decease susceptible population and prevent measles cases in infants before vaccination age(month),revaccination in unmarried women of child-bearing age is recommended.