Analysis of drug-resistance and examination on Acinotobacter producing extended-specturm β-lactamaes

  Objective   To analyze occurrence of extended-spectr um B-lactamases(ESBLs)of Acinetobacter isolated from patients with lower respiratory tract infection, and to detect the drug sensitivity to 10 kinds of antibacterial drugs.Finally a suggestion was given to treat lower respiratory tract infection due to A cinetobacter infection.

  Methods   156 strains isolated from clinical lower respiratory tract infections specimens were isolated and ESBLs were identified by the VIT EK ESBLs detection test and double-disk synergistic tests and standard disk diffusion test.The effects of 10 kinds of antibacterial drugs to strains were compared.

  Results   Occurance rate of ESBLs was 20.5%, and pr oductive rate of ESBLs in A.baumanii A.lw of fi, Haemolytius and A.calcoaceticus was 56.2%, 25.0%, 12.5% and 6.3% respectiv ely.

  Conclusion   Acinetobacter strains isolated form lower respiratory tract infection showed distince antibacterial resistance.Acinetobacter strains producing ESBLs could not be neglected.