Study on ecological epidemiology of Hantavirus reservoirs in Beijing city

  Objective   To identify the condition of Hantavirus infection and genetype as well as to determine the risk factors of hantavirus infection in rodents captured in Beijing and the relationship between them.

  Methods   The captured mice were classfied and the density of distribution was calculated.RT-PCR technique was used to amplify the partial M fragnments of Hantavir use.Several representative positive samples were sequenced and analysed by Clustal X(5.0)and DNAClub software.

  Results   A total of 295 animals were captured, among which Battus norvegicus was the dominant group.The median infection rates with hantav irus were 14.58% in Battus norvegicus and 2.33% in Mus musculus Linnaeus.Nucleotide sequences analysis showed that the virus detected all belong ed to SEO-type.The infection rates in the population which weighs more or has some scars in the body were higher.No significant difference of HV prevalence was recorded between male and female.

  Conclusion   The SEO-HV infection of rodents was widely distributed in Beijing and the nature focus of HT-HTV was not found.The major host of Hantavir use in Beijing was Rattus norvegicus.There was some correlations between the HV prevalence and the sub-population of rodents on sample sites.