Effects of high-selenium panax japonicus extracts on reducing blood lipid and antioxdation

ObjectiveTo study the effects of high selenium panaxjaponicus extracts on serum lipids and antioxidative enzyme in hyperlipidemic rats.MethodsThe hyperlipidemic model was established by feeding rats with high-fat diet.After 4 weeks the serum lipids and antioxidative enzymes content were determined respectively.ResultsCompared with the model,high-selenium panax japonicus extracts lowered the serum total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-c)malondialdehyde(MDA),increased high density lipoprotein cholesterol(HDL-c),total antioxidative capacity(T-AOC),superoxide dismutase(SOD)and glutathioneperoxidaes(GSH-Px)activities significantly(P<0.05 or P<0.01).ConclusionHigh-selenium panax japonicus extracts can lower the serum lipid level,enhance the antioxidation and inhibit the lipid peroxidation in the rats with hyperlipidemia.