Effect of calorie restriction on weight,level of fasting blood glucose and blood lipids in rats

Objective To study the effect of different levels of calorie restriction on blood glucose and lipids in rats.Methods Thirty-six male rats housed individualy were randomly divided into ad libitum group,calorie restriction group 1 and calorie restriction group 2.One group were fed with basic diet and the other two with 80% and 60% energy of AL-fedgroup respectively for 12 weeks,then changes of weight,blood glucose and lipids were tested.Results The body weight,visceral fat accumulation,body fat percent,level of HDL-C and T Gof calorie restriction group were significantly differenct from that of ad libitum group except for blood glucose.The level of TC in calorie restriction group 2 was not significantly higher than that of control group until the end of the test.Conclusion Calorie restriction can enhance the level of HDL-C,decrease TG and have no significant effect on the blood glucose.The level of TC is increased when the rats have less calorie intake at some point.