Relationship between serum leptin and simple obesity of teenagers in Lanzhou city

Objective To analyze the relationship between serum leptin concentration and simple obesity of teenagers.Methods The serum leptin concentration was measured by RIA in 998 teenagers in Lanzhou.Results There was a positive correlation between serum leptin concentration and BMI(r=0.310,P<0.01).In both girls over 10 years old and boys over 13 years old,the serum leptin concentrations of the obese groups were obviously higher than that of the normal weight and thinner(P<0.05).There was no correlation between the sex and the serum leptin concentration(r=0.030,P=0.374).But for subjects over 13 years old the sex differences had statistical significance(P<0.05).The serum leptin concentration and the age presented a negative correlation(r=-0.120,P=0.004).Conclusion The leptin and the obesity degree presented a positive correlation.There was leptin resistance among the obese teenagers.Serum leptin concentration could be regarded as an important evaluation index of teenagers' simple obesity.