Prediction and analysis for structure and function of adenylate kinase gene from Taenia solium by bioinformatics

ObjectiveTo analyze and predict the structure and characteristics of adenylate kinase gene from Taenia solium by bioinformatics for its biological function and application research.MethodsWith analyzing tools of bioinformatics in webs site and bioinformatics software package,adenylate kinase was recognized from the Taenia solium full-length cDNA plasmid libratory andits gene structure and coding region sequence was analyzed andits physical-chemical characteristics,topo logical structure and 3 Dstructure were predicted.ResultsThe full gene is 864 bp in length and its coding region is 110-758,coding 215 amino acids.It is a complete full-length gene comparing with the homologues in Gen Bank.The prote in has no transmem brane region.The molecular weight of adeny late kinase gene is predicted to be 23771.4Da.The proe in contains no transmem brane region and subcellular location sequecce.The predicted amino acid sequence shows 66% identity and 84% smiilarity with that of ADK form Schisto somaja ponicum.ConclusionThe cDNA sequence encoded adenylate kinase gene was screened from cDNA library of adult Taenia solium by bioinformatical method.The gene and prote in structure and characteristics of Taenia soliumadeny late kinase were obtained.