Prevalence and related risk factors of nonalcoholic fatty liver among administrative officials

ObjectiveTo investigate the prevalence of nonalcoholic fatty liver and its risk factors among a specific population in Fuzhou city.MethodsA total of 3 884 administrative officials who denied regular alcohol drinking participated in the survey Questionnaire survey, physical examination, serum lipid-profile, 75 gramoral glucose tolerance test and ultrasonogmphic examination of liverwere conducted.ResultsThe age-sex-adjusted prevalence of nonalcoholic fatty liver in the participants was 27.45%.The age-adjusted prevalence of nonalcoholic fatty liver in themale was 35.70% and significantly higher than that of in fem ale(17.47%,P<0.05).The prevalence of obesity, hypertension, dyslipidemia, high blood uric acid and low high-density lipoprotein cholesterol(HDL-C)in the nonalcoholic fatty liver group were significantly higher than those of in the group without fatty liver(all P<0.05).Multiple variant regression analysis showed that there were positive correlations between prevalence of nonalcoholic fatty liver and factors such as sex, age, obesity, hyperlip idemia, hypemricaemia,low HDL-C and inpaired glucose tolerance Conclusion There is a high prevalence of nonalcoholic fatty liver among administrative officials in Fuzhou.Metabolic disorders such as obesity, hyperlip idemia, and hyperuricaemis are significantly related to nonalcoholic fatty liver.