Effect of eye acupuncture on cerebral blood flow and velocity in rats with ischemia-reperfusion

ObjectiveTo observe the effect of eye acupuncture on cerebral blood flow and velocity in rats with cerebral ischemia reperfusion(ICRI)and to explore the mechanisms of eye acupunture treatment to cerebral ischencic diseases. MethodsLaser Doppler microcirculation measurement instrument was used to measure blood flow and velocity of cerebnal cortex in rats 24 hours after cerebral ischemia.The structural changes in the capillary loops of the cortex was observed with electron microscope. ResultsThe blood flow of cerebral cortex was 63.28±8.84 PU for ischemic model rats and 169.39±19.89 for the model rats with eye acupuncture,and the blood flow velocity was 19.98±6.75 mm/s for the model rats and 57.43±28.54 mm/s for the model rats with eye acupucture,respectively,with significant defferences between the two groups(P<0.01 for all).The ultrastructure of cerebral cortex capillary was normal for model rats with eye acupuntrre but necrosis and atrophy of capillary endothelial cells were observed in cerebral ischemic model rats. ConclusionEye acupucture can increase blood flow and velocity of cortex tissue in rats with ICRI and improve ultrastructure of the capillary endothelial cells in rats with ICRI.