Influencing factors of oral cancer：a case-control study

ObjectiveTo investigate the influencing factors of oral cancer and to provide reference for the prevention of oral cancer.MethodsThe subjects included 206 oral cancer cases and 584 age-and gender-matched controls recruited from local population.The odds ratios(ORs) and their 95% confidence interval(95% CI) of all factors which entered unconditional logistic regression model were calculated.ResultsSignificantly higher consumption ratios of meat(49.49% vs 26.21%),poultry meat(7.19% vs 1.46%),fish(47.43% vs 14.08%),seafood(33.56% vs 4.85%),green leafy vegetables(95.89% vs 87.38%),other vegetables(95.21% vs 79.13%),fruits(39.55% vs 15.33%),supplements(15.58% vs 6.31%),and vitamin supplements(15.92% vs 5.34%) were observed in the controls compared to those in the cases(P<0.05 for all) ;the proportion of smoking(50.97%),alcohol drinking(40.29%) and oral diseases(5.34%) in case group were higher than those in the controls(29.62%,20.72% and 1.54%).Multivariate unconditional logistic regression analysis indicated that seafood,other vegetables,and fruits were protective factors of oral cancer,whereas smoking,alcohol drinking and oral diseases were risk factors for oral cancer.ConclusionSeafood,other vegetables,and fruits consumptions may reduce the risk of oral cancer,but smoking,alcohol drinking and oral diseases could increase the risk of oral cancer.