Association between dietary pattern and nonalcoholic fatty liver disease in female population in Jinan city

Objective To explore the relationship between different dietary pattern and nonalcoholic fatty liver disease(NAFLD)and to provide the reference for the prevention and control of NAFLD in female population of Ji'nan city.Methods Totally 1 354 women having a physical examination in a 3A grade hospital in Ji'nan from November 2010 to July 2012 were randomly selected for a dietary survey and anthropometric and biochemical measurements.Factor analysis and multivariate logistic regression model were used to analyze the association of dietary patterns with NAFLD.Results The detection rate of NAFLD in the female population was 8.4%.Five dietary patterns,namely meat and fish,grains and vegetable,oil cereals,pastries beverage,and eggs and milk pattern,were identified through factor analysis,with a cumulative variance contribution rate of 50.54%.After adjusting for age and body mass index(BMI),multiple logistic regression analysis showed that meat and fish pattern(odds ratioOR=0.49,95% confidence interval95% CI:0.28-0.87)and pastries beverages pattern(OR=1.84,95%CI=1.07-3.14) were associated with NAFLD.Furthermore,dietary pattern scores were categorized into quartiles to conduct multivariate logistic regression analysis.After adjustment for age and BMI,the results displayed that the females in the highest quartile for the meat and fish dietary pattern had a 5.00 times greater odds of NAFLD(OR=5.00,95% CI 1.04-23.90)compared with those in the lowest quartile.The females in the second quartile of oil cereals pattern scores had a lower risk of NAFLD(OR=0.38,95% CI=0.38-0.90)compared to those in the lowest quartile of the score.The females in the third quartile of pastries beverage pattern scores had a lower risk of NAFLD(OR=0.36,95% CI=0.36-0.99)compared to those in the lowest quartile of the score.Conclusion Excessive intake of fish and shrimp,poultry meat,cakes and beverages may increase the risk of NAFLD in female population.