Risk factors of hemorrhagic infraction among the elderly:a case-control study

ObjectiveTo explore the risk factors of hemorrhagic infarction(HI)among senile people and to provide evidences for the prevention of HI among the elderly.MethodsIn this study,96 HI patients confirmed by head computer tomography(CT)or magnetic resonance image(MRI)and treated in a hospital from October 2011 to October 2012 were selected as HI group and 101 acute cerebral infarction patients with hemorrhage were selected as the control group.The data on clinical manifestation at the hospital admission and disease history of the cases and controls were collected and analyzed with descriptive method and multivariate logistic regression.ResultsFor the cases,the ratio of massive cerebral infarction and cerebral embolism was 62.5% and 43.75% ;the most common hemorrhagic site was cerebral cortex(75.00%),followed by basal ganglia temporal lobe(9.38%),parietal lobe of basal ganglia(9.38%),and cerebellum(9.38%);87.5% of the patients had patchy hemorrhage bleeding and 12.5% had hematoma formation.Univariate analysis revealed that the risk factors of HI were cerebral embolism,cortical infarction,extensive infarction,diabetes mellitus,high blood sugar,history of hypertension,history of heart disease,Trial of Org 10172 in Acute Stroke Treatment(TOAST)classification,and Glasgow Coma Scale(GCS) score (all P<0.05).Logistic regression analysis showed that cerebral embolism,cortical infarction,extensive infarction,hyperglycemia at the admission,and hypertension were independent risk factors for the onset of HI.ConclusionThe incidence of HI is related to the type of cerebral infarction,the size of cerebral infarction,the location of cerebral infarction,blood pressure,and blood sugar.