Polymorphism of HOXA10 gene among female infertility patients

Objective To explore the polymorphism of HOXA10 gene among female infertility patients in Hainan province.Methods We selected 220 female infertility patients seeking medication in a hospital during 2013 July to July 2014 and collected their venous blood samples for genomic DNA extraction and analysis of single nucleotide polymorphism (SNP) of rs3779456 of HOXA10 gene.Results The frequencies of CC,CT,and TT of rs3779456 of HOXA10 were 36.36%,20.91%,and 42.73% among patients and the allele frequency of C and T were 46.82% and 52.18%.Conclusion There are three genotypes for 2 alleles of rs3779456 of HOXA10 gene among female infertility patients in Hainan province.