Curative effects of different therapeutic regimes in patients with neurogenic bladder dysfunction

Objective To compare curative effects of different therapeutic regimes in patients with neurogenic bladder dysfunction. Methods Totally 64 inpatients with neurogenic bladder dysfunction were recruited and assigned equally into an observation group (group A)administered with sacral nerve stimulation and bladder function training and a control group (group B)with bladder function training in the Affiliated Hospital of Hainan Medical College from March 2013 to October 2014.We assessed urinary flow dynamics, bladder pressure, residual urine volume for the inpatients before and after the treatments. Results The indicators changed after the treatments among all the inpatients.The average urinary flow rate increased and the average residual urine volume decreased among the inpatients with chronic urinary retention.For the patients with detrusor hyperactive disorder, the average number of urination, urinary incontinence, and night urination decreased and the average maximum intravesical pressure declined but the average maximum bladder capacity increased after the treatments (P < 0.05).The average residual urine volume of the chronic urinary retention patients in group A was significantly lower than that of the patients in group B(41.2±13.6 vs.128.6±43.9 ml, P < 0.05);the average micturition frequency of the inpatients with detrusor hyperactive disorder in group A was significantly lower than the inpatients in group B (6.67±2.2 vs.9.53±3.17 per day, P < 0.05).The indicators among the patients of group A showed better improvement than those among the patients of group B. Conclusion Sacral nerve stimulation combined with bladder function training can effectively improve micturition frequency, urgent urination, incontinence of urine and urine flow dynamic characteristics among the patients with neurogenic bladder dysfunction.