Objective To Study the influence of excessive calcium supplyment on the growth of rats, metabolize of calcium and lever of iron and zinc.
Methods 40 weaned Wistar rats were divided randomly and equally into 4 groups according to the weight. One of them was background group which was killed before fed. The others were fed by different calcium content for 28 days then were engaged in metabolize of calcium experiment.
Results Rats' growth were influenced by the different calcium content, which inclued rats' weight gained slowly. The weight of the thighbone was increased but the length of it wasn't increased. The bone were calcified too early by excessive calcium intake. Excessive calcium intake made the viscera coefficient of rats changed, and had certain harm to testicle and kidney and so on. The absorbability and using of calcium were decreased, which wasted calcium and increased metabolizable burden of body. At the same time, it made the concentration of serum zinc and serum iron depressed, but the serum calcium went up. High uric calcium was the latent dangerous factor of nephrolith.
Conclusion The excessive calcium influenced the growth of rats and harmed certain viscera. And it disturbed the absorbability and using of calcium, iron and zinc.
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