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LI Tao, HUANG Lianzhen, GAO Weiwei, . Protective effects of zinc or/and vitamin E supplement on edothelial cells in diabetic rats[J]. Chinese Journal of Public Health, 2005, 21(1): 69-70.
Citation: LI Tao, HUANG Lianzhen, GAO Weiwei, . Protective effects of zinc or/and vitamin E supplement on edothelial cells in diabetic rats[J]. Chinese Journal of Public Health, 2005, 21(1): 69-70.

Protective effects of zinc or/and vitamin E supplement on edothelial cells in diabetic rats

  •   Objective   To study the protective effects of zinc and vitamin E on oxidative stress and endothelial cells in STZ-induced diabetic rats.
      Methods   Streptozotocin-induced diabetic rats were supplemented with zinc and vitamtn E for six weeks.Blood glucose, insulin, MDA and T-AOC in serum, plasma levels of TXB2, 6-k-PGF and ET were examined.
      Results   In diabetic rats plasma levels of TXB2 and ET were lowered while blood glucose and MDA were decreased, insulin, T-AOC and plasma levels of 6-k-PGF were increased by zinc and vitamin E supplement.
      Conclusion   Zinc and vitamin E supplementation reduced oxidative stress, influenced the plasma levels of TXB2, 6-k-PGF and ET, and had protective effects on endothelial cells in diabetic rats.
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