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CHEN Yue, LI Sheng. Study on relation between renal damage and calcium homeostasis in cadmium-poisoned wistar rats[J]. Chinese Journal of Public Health, 2004, 20(9): 1065-1066.
Citation: CHEN Yue, LI Sheng. Study on relation between renal damage and calcium homeostasis in cadmium-poisoned wistar rats[J]. Chinese Journal of Public Health, 2004, 20(9): 1065-1066.

Study on relation between renal damage and calcium homeostasis in cadmium-poisoned wistar rats

  •   Objective   To study the cell molecular mechanism of cadmium-induced renal damage.
      Methods   With Cadmium dose 1.4 mg/kg Cd2+ by celiac injection to make renal damage model in order to observe relation between renal damage and changes of intracellular calcium content.
      Results   The content of protein, N-acetyl-β-glucosaminidase in urine increased continually, GFR decreased, the intracellular calcium increased relatively.
      Conclusion   The damage of intracellular calcium homeostasis leaded to the renal function disorder.
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