Effect of ahylysantinfarctase therapy for severe frostbite on blood visible component

  Objective   To observe effect of ahylysantinfarctase combined therapy for severe frostbite feet on blood visible component and to explore the therapeutic mechanism.

  Methods   Severe frostbite model was made and ahylysantinfarctase combined therapy was used.Five indexes of blood visible component extracted from rabbit were determined before and at eight-time point after frostbite for 6 weeks.

  Results   WBC count was recovered to normol level in one week; RBC count, HGB, Het were recovered to normol level at 48 h or 72 h; Plete count was drop but there were not accidently defferece compared with group Ⅰ at 24 h after frostbite during ahylysantinfarctase combined therapy was administered.The five indexes of group Ⅰ recovered to normal level in 3-4 weeks after frostbite.

  Conclusion   The blood circulation was improved obviously and inflammation was resisted and prevented effectively.The pathological change was promoted by using ahylysantinfarctase combined therapy.