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LIU Ying, LU Lin, DONG Ji-sheng, . Effect of genistein on iNOS expression and anticancer in human breast carcinoma cells[J]. Chinese Journal of Public Health, 2004, 20(4): 395-396.
Citation: LIU Ying, LU Lin, DONG Ji-sheng, . Effect of genistein on iNOS expression and anticancer in human breast carcinoma cells[J]. Chinese Journal of Public Health, 2004, 20(4): 395-396.
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Effect of genistein on iNOS expression and anticancer in human breast carcinoma cells

    Abstract
  •   Objective   To study the genistein on the effect of proliferation and the iNOS expression of human breast car-cinoma MCF-7 cells.
      Methods   MTT was used to investigate the effects of genistein in breast cancer cell proliferation.Immunocytochemstitry and RT-PCR were used to observe the effects of genistein on iNOS gene expression.
      Results   Genistein inhibited the proliferation of tumor cells significantly and increased iNOS protein expression.
      Conclusion   Proliferatory inhibition of human breast carcinoma cells after being treated with genistein may be due to the up-regulation expression of iNOS.
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