Objective To observe the immunotoxicologic effects of transgenic rice on mice.
Methods The Balb/c mice were divided into four groups, transgenic rice group(Xa group), non-transgenic rice control group(N group), AIN93G control group(A group)and positive control group(P group).The mice were fed with corresponding food for 30 days.The immunity indicators of mice were compared.
Results The indicators were as fellows: body weight, blood routine test, lymphocyte sort, lymphocyte transform test, immunity organ index, delayed hypersensitivity response, antibody forming test, serum antibody titter, macrophage function test and NK cell activity test.All indicators between Xa group and N group were no statistic difference.The spleen index and NK cell activity in Xa group were higher than those in A group and the other indicators were no statistic difference each other.Most of all indicators in P group were lower than that in the other groups.
Conclusion The immunotoxicologic effects of transgenic rice on mice were safe.
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