Objective To investigate the related factors of serum NPY level in children with simple obesity.
Methods Serum NPY level was measured by radioimmunological simple obesity children aged 6-13.
Results No relationship was observed between serum NPY level and age.No different NPY level was found between the male and female.NYP level was increased significantly in moderate and severe obesity than that in mild one, corr elated positively with body weight.And NPY level elevated with the increase of body weight.NPY level in children with hyperlipidimia or family obesity history increased significantly than that in without.Children with a high frequency of food intake and long obesity history(≥5 years)elevated NPY levels than those with normal frequency and short history(< 3 yeas).
Conclusions Serum NPY level in simple obesity children was related to body weight, family obesity history, frequency of food intake and the course of obesity, but not to age and sex.
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