LI Wei-dong, ZHANG Ming-lei, PU Yun-feng. Study on inhibiting effect of ATRA and cisplatin on human hepatoma cell[J]. Chinese Journal of Public Health, 2004, 20(4): 459-460.
Citation:
LI Wei-dong, ZHANG Ming-lei, PU Yun-feng. Study on inhibiting effect of ATRA and cisplatin on human hepatoma cell[J]. Chinese Journal of Public Health, 2004, 20(4): 459-460.
LI Wei-dong, ZHANG Ming-lei, PU Yun-feng. Study on inhibiting effect of ATRA and cisplatin on human hepatoma cell[J]. Chinese Journal of Public Health, 2004, 20(4): 459-460.
Citation:
LI Wei-dong, ZHANG Ming-lei, PU Yun-feng. Study on inhibiting effect of ATRA and cisplatin on human hepatoma cell[J]. Chinese Journal of Public Health, 2004, 20(4): 459-460.
Study on inhibiting effect of ATRA and cisplatin on human hepatoma cell
Objective To investigate the mechanism of effect of A TRA and cisplatin on telomerase activity and proliferation of hepatoma.
Methods Cell culture, morphology MTT calorimetric assay and TRAP assay.
Results ATRA is the only one that can inhibit telomerasa activity, all agents can inhibit the proliferation of hepatoma, the inhibitory effect of cisplatin is the strongest.
Conclusion ATRA can inhibit obviously telomerase activity of hepatoma cells.
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