Correlation between pesticides exposure and morbidity and mortality of breast cancer

  Objective   To make sure whether there is significant correlation between environmental pesticides exposure and breast cancer morbidity or mortality in agricultural women.

  Methods   To collect both using data of pesticides in suburban areas from 1990 to 2000 and breast cancer morbidity and mortality data of Shenyang in 2000.To regard pesticides using density of 11-year aver age as independent variable, age-group breast cancer morbidity and mortality as dependent varible, respectively.The coefficients of rank corrleation and linear regression between pesticides exposure and breast cancer morbidity and mortality are carried out by spss 10.0 statistical software.

  Results   The positive significant correlation is observed between pesticides using density and breast cancer morbidity and mortality in people of 35-64 age group, respectively.The coefficients of correlation and P value are 0.829(0.042), 0.943(0.005), respectively.Further analysis finds that 50-59 age group morbidity and 40-49 age mortality has significant positive correlation with pesticides using density.The coefficient of correlation and value are 0.829(0.042), 0.886(0.019), respectively.Simple regression analysis finds that significant doseresponse relation exists between 35-64 age mortality and pesticides using density.The regression coefficient is 4.448(P < 0.05).

  Conclusion   Environmental pesticides exposure is relative to morbidity and mortality of breast cancer in agricultural women.Linear relation is significant between 35-64 age mortality and pesticides using density.