Objective To study the effects of plumbum(Ⅱ) or cadmium(Ⅱ) on DNA damage of germ cells of male mice in vitro.
Methods The DNA damage was observed by means of SCGE assay.
Results Different dose plumbum(Ⅱ) or cadmium(Ⅱ) could cause DNA damages in male mice germ cells and there was significant dose-effect relationship.
Conclusion Plumbum(Ⅱ) or cadmium(Ⅱ) could cause DNA damage of germ cells in vitro.