Objective To establish a model of oxidative damage in erythrocycte ghost induced by superoxide anion free radicals(SAFR), and to study the influence of portulaca total flavone on erythrocyte ghost blocking degree.
Methods the erythrocyte ghost oxidative damage was induced by SAFR which was produced by auto-oxidation of pyrogallicacid.The effect of portulaca total flavone on erythrocyte ghost blocking degree was studied.
Results SAFR can apparently alleviated blocking degree.But portulaca total flvone improved the membrance blocking degree significantly, and there was dose-effect relationship.
Conclusion Portulaca total flavone had certain protective action for erythrocyte ghost blocking degree.