Objective To investigate the relationship between the CD4/CD8 cell levels and the plasma viral load in HIV -infected people.
Methods The viral load of 207 blood samples of 84 cases were tested.The CD4/CD8 cell levels of 491 blood samples of 194 cases were tested.11 of HIV-infected cases were followed up at regular intervals and their viral load and CD4/CD8 cell levels were tested.The data were analyzed statistically using SPSS software to explore the trend and correlations.
Results There are significantly negative correlation trend between the CD4 cell levels and viral load(r=-0.576, P < 0.01).Close correlation were observed between the CD4/CD8 ratio and the viral load(r=-0.544, P < 0.01).The CD8 cell levels were also low in the cases with low CD4 cell levels.With the lossing of CD4 cells, the CD8 cell levels would descend.
Conclusion The CD4 cell levels and the ratios of CD4/CD8 were useful indicators to viral load.In the cases with low CD4 cell levels, the changing trends of the CD4 cell levels and viral load were reverse, but not synchronous.
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