Objective To study the effect of NaF on proliferation of nephrocyte and protective efficiency of VE, Vc, Se and GSH.
Methods Adding different concentrations of NaF, VE(25μmol/L), Vc(50μmol/L), Se(5μmol/L)and GSH (1mmol/L)into cultured nephrocyte using ELISA to determine the level of OD, and computing the proliferation rate of nephrocyte.
Results NaF has two-side action on the proliferation of nephrocyte.
Conclusion VE, Vc and GSH can antagonize the toxic effect of NaF(1 mmol/L)on nephrocyte.