Analysis on high risk factor of newborn congenital syphilis in Shenzhen

  Objective   To investigate the high risk factor of newborn congenital syphilis.

  Methods   53 positive and negative pairs of new borns and their mothers were selected as case group and control group of observation by rapid plama reagin circle care test(RPR)and treponema pallidum particle agglutination(TPPA).

  Results   Only 12 sick mothers(22.6%)in case group had antenatal care and syphilis screening, the number was significantly lower than that of the control group (100.0%, χ²=66.861, P < 0.01)and all were pregnant syphilis.Seven mothers in case group had the treatment after 20-week pregnancy(χ²=3.087, P < 0.05), while three mothers in control group who suffered syphilis had thorough treatment before 20-week pregnancy and the rates of the accurate answer on having the antenatal care and early treatment or stopping pragnance were significantly lower than those of the control group(U=5, 408, χ²=29.754 and 10.82, P_ar=0.01).

  Conclusion   Without enough health education, regular syphilis screening in pregnance and intervention in early stage were high risk factors of new born congenital syphilis.