Analysis on CMV infection during pregnancy in Qinba mountainous areas

  Objective   To study the epidemiology of CMV infection in Qinba mountainous area with higher prevalence of mental retardation in children.

  Methods   Three hundred and sixty-seven pregnant women were monitored with ELISA and PCR and presented with questionnaire.CMV-DNA in urine of 63 neonates within two weeks, whose mother infected CMV during pregnancy and CMV-DNA in breast milk two weeks after delivery of 61 women infected and 84 women non-infected were detected.

  Results   Infection rate of CMV in mental retardation prevalent areas was 19.62%, the incidence of transmission in utero was 33.33%.The incidence of excretion by breast milk was 39.02%.CMV infection during pregnancy related to age, education, economic states, pregnant frequency and pathological delivery.It had no relation with gestational age.

  Conclusion   CMV detection in mental retardation prevalence areas should be paid much attention.Less education, worse financial condition, more frequent and pathological delivery should be regarded as high risk factors of CMV infection during pregnancy.