Effect of pregnancy complicated syphilis on perinatal prognosis

  Objective   To find the epidemic feature of pregnant syphilis and to explore the effective way to decrease the influence on the perinatal.

  Methods   To make a retrospective study on 41 patients diagnosed after being screened by syphilis rapid plasma reponse test(RPR)and treponema pallidum puticulate agglulinate test(TPPA)from 1997 to 2002.To use penicillin in the whole treatment and make a trail.

  Results   Among the patients, the juniors and unemployees occupied 85%.The rate of their husbands with syphilis was 100%, including 29.3% Hongkong residents.Pregnant insidious syphilis 97.5%, 6519% patients were diagnosed in week 20 of pregnancy and 58.5% were treated.The death rate of the perinatal in treated group(0.0)and congenital syphili rate(8.0%)were lower than untreated group(58.5% and 85.7%, P_ar < 0.01).

  Conclusion   Pregnancy complicated syphilis had severe influence on death of the perinatal, which was an important factor on spreading congenital syphilis.So, it is important to find early and have a whole treatment.Enhancing the pregnant safe behaviors wasthe useful method to aviod being reinfected.