Case-control study on risk factors of schizophrenia

  Objective   To investigate the main risk factors of schizophrenia in Xi'an as so to take theoretic foundation to reduce mental illness.

  Methods   A case-control study was conducted to analyze the main risk factors by univariate and multivariate analyses respectively in 101 first episode pattents with sohizophrenia and 101 normal controls.

  Results   Four risk factors, positive family history of psychosis(OR=7.98, 95% CI=2.58-32.58), introversive characters(OR=3.32, 95% CI=1.60-6.94), psychosis traumatic events(OR=5.68, 95% CI=2.01-15.63)and tense relationship with parents(OR=4.27, 95% CI=1.03-17.74)had significant correlation with schizophrenia.

  Conclusion   The development of schizophrenia was caused by both genetic factors and various environmental factors.