Preparation of fiber complexes and its role in prevention of atherosclerosis

  Objective   To prepare the artificial fiber complexes and examine its role in lipid content in comparison with other three single fibers in hyper lipidemia rats.

  Methods   Forty-eighthealthy, female Wistar rats(50-80g)were randomly divided into six groups based on body weight.All five kinds of DF(cellulose-group B, pectin-group C, sodium alginategroup D, cellulose-pectin complex-group E, cellulose-sodium alginate complex-group F)were given at a level of 10% in the diet fed on a lipid-rich diet.The control group(group A)was fed on a lipid-rich diet alone without DF.A fter eight weeks, the effect on growth and development and lipid metabolism in rats were studied.

  Results   (1) Five kinds o f DF did not affect the growth and development of the expreimental rats.(2)Compared with the control group, all DF groups can lower lipids, especrial fiber complexes.(3)The fecal weight and fat contents in all DF groups were significantly higher than that in control group, especially for fiber complex groups.(4)There were obviously correlation between serum lipids and fecal fat contents.

  Conclusion   These kinds of DF had the effect of lowering lipids to so me extent in rats, and fiber complexes were more effective than single fibers.