Effects of paradichlorobenzene on experimental allergic conjunctivitis

  Objective   To study the effect of paradichlorobenzene on the allergic conjunctivitis.

  Methods   The effects of different concentrations of paradichlorobenzene were observed by quantitatively measuring the conjunctivitis, which was based on the model of anti-cedar-pollen serum induced allergic conjunctivit is in guinea pigs.

  Results   The allergic conjunctivitis was apparently aggr avated when the concentration of paradichlorobenzene was over 4.1 μg/m³ in the air, and most intensive aggravating effect was obtained at a dosage of 41 μg/m³ paradichlorobenzene, which persisted for more than 1 week.

  Conclusion   The paradichlorobenzene had the effect of immunotoxicity, and apparently agg ravated allergic conjunctivitis at lower concentration.