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QIN Hai-hong, GUO Jun-sheng, ZHAO Fa-ji. Effect of Fe on viability of heat-exposed K562cell and their hSP70 contents[J]. Chinese Journal of Public Health, 2003, 19(1): 4-6.
Citation: QIN Hai-hong, GUO Jun-sheng, ZHAO Fa-ji. Effect of Fe on viability of heat-exposed K562cell and their hSP70 contents[J]. Chinese Journal of Public Health, 2003, 19(1): 4-6.
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Effect of Fe on viability of heat-exposed K562cell and their hSP70 contents

    Abstract
  •   Objective   To study the effects of Fe on viability of heat-stressed K562 cell, HSP 70 and its probable mechanisms.
      Methods   K562 cell were cultured with RPMI-1640 medium added with Fe at variant concentrations, then the cell viabilities of K562 and the contents HSP 70 were detected after heat exposure.
      Results   A certain concertration of Fe2SO4(100-400 μmol/L), critric acid iron(100-200 μmol/L)could enhance viabilities of heat-exposed K562 cell and their synthesis of HSP 70.
      Conclusions   These findings suggested that Fe could significantly promote thermoresistance of K562 cell, and some of their mechanisms might due to the enhancing synthesis of HSP 70.
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