An Study of Coxsackie Virus B Infection and The Relationship between Coxsackie B and hepatitis Virus Infection

An investigation of relationship between coxsackie virus B(CVB) and hapatitis virus infection have been carried out in 121 clinical hapititis patients and 108 donors by testing serum anti-CVB-IgM and anti-CVB-IgG with immuno-enzmye histoch emical method. The results shows that:the positive rate of anti-CVB-IgM,IgG,and IgM+ IgG is 9.9%,19.8%,25.6% in hapatitis group,and 8.3%,36.1%,40.7% in donors groupres pectively;the three positive rate as above is 663%,15.9%,20.6% hapatitis B group,and 13.8%,24.1%,31.0% in non-B hepatitis group respectively,in hepatitis group,especiaiiy in hepatit is B group,the positive rate of anti-CVB-IgG, and IgG+ IgM is significantly lower than donor group. These results indicated that the hepatitis B patients may have low immune response to CVB,or the hepatitis B virus may in terfere the CVB infections ubsequently.The detail lmechanism need fur ther study.