Effect of Nano-zinc powder on mice serum biochemical indexes

  Objective   To explore the effect of Nano-zinc powder on mice serum biochemical indexes.

  Methods   The mice were treated by one single oral dose of nano-zinc or micron-zinc powder at 5 g/(kg·bw).After 14 days, the mice were sacrificed and the serum were collected for biochemical analysis.

  Results   In Nano-zinc group, only the serum LDH, HBDH were obviously higher than that in control group(P > 0.05), but in micron-zinc powder group, the serum LDH, HBDH, ALT, ALP, CHE, LAP, TP, ALB, AST, UA, BUN, Ca, P, TG were higher significantly than that in control group(P > 0.05).The serum LDH, HBDH, ChE, LAP, TP, ALB, Ca of Nano-zinc group were lower than those in micron-zinc powder group significantly(P > 0.05).

  Conclusion   In general the Nano-zinc has difference effect on mice biochemical indexes as compared with the micron zinc powder.