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2013 Vol. 29, No. 10

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Association between MS and cardio-cerebrovascular disease and total mortality in Inner Mongolian population
ZHANG Yan-fen, TONG Wei-jun, LIU Yang.et al
2013, 29(10): 1405-1409. doi: 10.11847/zgggws2013-29-10-01
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Objective To analyze the association between metabolic syndrome(MS)and cardio-cerebrovascular disease and total mortality.Methods A 8-year follow-up study was conducted among 2 589 Mongolian people aged 20-84 years.The observed outcomes were cardio-cerebrovascular disease(stroke and coronary heart disease)and total mortality.Multivariate proportional hazards model was adopted to analyse the hazard ratios(HR)and their 95% confidence intervals(95%CI)of MS and other risk factors for multilple outcomes.Results Among all participants,the lost to follow-up rate was 0.23% and the total follow-up person-years were 18 543.There were 261 incidences of cardiovascular and cerebrovascular diseases observed.During the follow-up,the incidence density of stroke and coronary heart disease were 533.9/100 000 and 253.5/100 000 person-years,respectively,and the mortality density was 620.2/100 000 person-years.After djusting for age,gender,and the history of hypertension,multi-factor proportional hazards model analyses showed that MS was associated with the outcome,with the HR(95% CI)of 1.33(1.02-1.74)(P=0.034).ConclusionMS may increase the risk of cardiovascular disease and total mortality by 33% in Mongolian population,suggesting MS could predict the incidence of cardiovascular disease and death.
Influencing factors of illness incident during summer hot spell among bus drivers in Jinan city
ZHOU Lin, XIN Zheng, BAI Li.et al
2013, 29(10): 1410-1412. doi: 10.11847/zgggws2013-29-10-02
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Objective To explore the influencing factors of illnesss incident during summer hot spell among bus drivers in Ji'nan city,and to provide basis for implementation of health protective measures.Methods With quota sampling method,a self-administered anonymous questionnaire survey was conducted among 532 bus drivers from Ji'nan Public Transportation Company in September,2012.Results Overall 310(58.3%)bus drivers had illness experiences during the hot time.The differences in prevalence rates among the drivers of different gender,age,with different disease history,health status,monthly income,education background,work years,and bus type were statistically significant(P<0.05 for all).Multiple logistic regression analyses showed that females and chronic disease history were risk factors for illness incident during hot period,with the odds ratios(ORs)of 1.787 and 2.466.The drivers with general,good/very good health status were less likely to fall ill during hot spell than the drivers in poor/very poor health condition,with the ORs of 0.334 and 0.111;the air conditioning system in the bus contributed to reduce the risk of illness incident during hot spell,with an OR of 0.675.ConclusionGender,chronic disease history,health status,and bus type are influencing factors of illness incident among bus drivers in Ji'nan city during hot spell.
Prevalence of tuberculosis and its risk factors among patients with type 2 diabetes
ZHAO Wen-jing, SHI Li-zheng, Vivian A Fonseca.et al
2013, 29(10): 1413-1416. doi: 10.11847/zgggws2013-29-10-03
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Objective To examine the prevalence of tuberculosis and its risk factors in diabetic patients for earlier tuberculosis diagnosis.Methods Stratified-cluster random sampling was used to select 4 085 diabetic patients in Ningyang and Yishui county.Tuberculosis diagnosis and questionnaire survey were conducted in the diabetic patients.Relationship between tuberculosis and related risk factors among the diabetic patients were evaluated using logistic regression analysis.Results Totally 14 tuberculosis cases were diagnosed among the 4 085 diabetic patients.The prevalence of tuberculosis in the patients was 342.72/100 000,compared to 42.82/100 000 in the general population.Patients with comorbid diabetes and tuberculosis were more likely to be male,underweight,anxious(P<0.05 for all)and to have cough,fever,hyperthermia,fatigue in past 24 hours and cough,expectoration and hyperthermia in past one month(P<0.05 for all).ConclusionDiabetic patients have a higher rate of developing tuberculosis.Male,underweight and anxious diabetic patients are more likely to have tuberculosis.
Delivery conditions and pregnancy outcomes among HIV-infected pregnant women in high AIDS incidence areas of China
WANG Qian, WANG Lin-hong, FANG Li-wen.et al
2013, 29(10): 1417-1419. doi: 10.11847/zgggws2013-29-10-05
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Objective To examine delivery conditions and pregnancy outcomes among human immunodeficiency virus(HIV)infected pregnant women.Methods This study was a prospective observational cohort study.From 2005-2011,1 187 HIV infected mothers and 1205 newborns were investigated face to face in 7 counties or districts with high HIV prevalence.Results Among the 1 187 pregnant women,hospital delivery accounted for 96.0%(1 139/1 187).The ratio of cesarean section among the women was 39.1%(456/1 166).The rate of pregnancy complications decreased from 34.1% to 24.3% from 2005 to 2011(χ2=6.856,P=0.009).Neonatal death rate was between 0 and 0.5%.There were no siginificant differences observed in annual variation trend for delivery status and pregnancy outcome among the HIV-infected pregnant women.ConclusionAlthough maternal delivery outcome and neonatal health being improved continuously,the incidences of some obstetric factors such as cesarean delivery,obstetric risk operation,pregnancy complications which may increase the risk of mother-to-child transmission are still high.
Evalnation on efficiency of different types of community health service with DEA model
MAO Yan-na, LIU Li-hang, WANG Xiao-wan
2013, 29(10): 1420-1424. doi: 10.11847/zgggws2013-29-10-06
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Objective To evaluate the delivery efficiency of different type of community health service(CHS)provided by community health system among 14 cities in Hunan province,and to provide reference for improving the delivery efficiency and quality of CHS.Methods The delivery efficiency of different types of CHS was evaluated with five data envelopment analysis(DEA)molds with the input and output data collected from performance evaluation survey on national primary public health service and statistics of health departments in Hunan province in 2011.Results For the primary health care,3 out of 14 CHS systems at city level were efficient according to DEA,with the overall efficient rate of 21.4%.The situation of maternal and child health was the same as that of primary health care.For the management of chronic diseases,4 out of 14 CHS systems were efficient according to DEA,with the overall efficient rate of 28.6%.For the prevention and health promotion,5 out of 14 community health service systems were efficient according to DEA,with the overall efficient rate of 35.7%.ConclusionThe results suggest that there is a need to promote medical skill,technical resource allocation,and establishment of effective stimulating policy for the improvement of delivery efficiency of CHS.
Impact of injury related deaths on trend of life expectancy
ZHANG Yu-long, JIN Ya-qing, ZHANG Yi-ying.et al
2013, 29(10): 1425-1429. doi: 10.11847/zgggws2013-29-10-07
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Objective To study the long-term trend of injury related deaths,the distribution of causes of injuries as well as the impact of injury related deaths on life expectancy in Jiading district,Shanghai,from 1985-2011.Methods Data were collected from vital statistics and registration system of Shanghai.Mortality level,main causes of death during the period were described.Time trend of death was analyzed and annual percentage changes(APCs)were estimated.Data related to cause eliminated life expectancy(CELE)and years of potential life lost(YPLL)were also calculated.Results The average crude death rates of injury during the period was 56.28/100 000 and injuries accounted for 7.81% of all deaths,ranking the fourth among the main causes of death for local population in Jiading.Injury was the first cause of death for the residents aged 1-39 years.Traffic accident,fall,suicide,drowning,and suffocation were the five top causes of injury.The death rate of traffic accident rose from 1993 and decreased from 2005 while fall showed a rising trend from 1994 with an APC of 6.35%.During the 27 years,the average years of life expectancy lost due to injury in the males and females was 1.28 and 1.13,respectively,and the average YPLL due to injury was 1 208.16 person years per 100 000.The average proportion of YPLL due to injury on total deaths was 20.13%,while YPLL due to injury decreased annually.ConclusionThe trends of mortality rates for injuries were declining,while the diseases of circulatory system and neoplasms were still the primary causes of death among the population of Jiading district.Injury is still the main death cause for young people,and the highest priority of injury prevention should be given to fall and traffic accident.
Parental knowledge on measles and its influencing factors in China
CHANG Jie, MENG Qing-yue, LIU Xiao-yun.et al
2013, 29(10): 1430-1432. doi: 10.11847/zgggws2013-29-10-08
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Objective To examine the knowledge level of measles and its influencing factors among parents,and to provide information for measles control and eradication.Methods Totally 3 609 parents of 1-6 years old children from 6 provinces were selected with random cluster sampling and interviewed during August to September in 2011.Results The overall good cognition rate of the parents was 87.4%(2 949/3 374).The good recognition rates were 94.9%(1 075/1 133),87%(988/1 105),and 80.8%(886/1 105)for the parents from eastern,central,and western region of China.The good recognition rates for the parents from city and rural were 91.3%(728/797)and 86.2%(2 221/2 577).Difference test showed that parental knowledge disparities between urban and rural,living area,gender,education groups,occupation and income groups were statistically significant(P<0.05 for all).The difference in parental knowledge between age groups was also statistically significant(χ2,P=0.011);with the increase of age,the knowledge on measles decreased.The results of logistic regression analysis showed that living area,gender,education,and living in centralarea were influencing factors for parental knowledge on measles.ConclusionMore attention should be paid to infectious diseases related health education for people living in western and central regions of China,rural areas and those economy vulnerable and with low education.
Establishment of norm for 16PF among Uighur police in Xinjiang
ZHANG Miao
2013, 29(10): 1433-1437. doi: 10.11847/zgggws2013-29-10-09
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Objective To establish the norm of Cattell's of 16 Personality Factor Questionnaire(16PF)of Uygur Version and to assess the reliability and validity of the 16PF among Uighur police.Methods The 16PF of Chinese version was translated into Uygur version.Using stratified random sampling method,218,172,and 3 817 Uygur police were selected from 15 prefectures in Xinjiang Uygur Autonomous Region for prediction,test-retest,and real test,respectively.The reliability and validity of 16PF Uygur version were analysed and the norm of the 16PF was constructed.Results The total score of Uygur version 16PF was correlated with the scores of most of the items with the coefficients of 0.415-0.689(P<0.01 for all).The questionnaire presented a good degree of differentiation.The overall internal consistency coefficient of the questionnaire was 0.827,the half reliability was 0.782,and the retest reliability was 0.600,indicating good reliability of the questionnaire.The validity test showed that every personality item could efficiently reflect its factor and the correlation coefficients among the 16 personality factors ranged from-0.375 to 0.459,with every factor being independent of other factors,demonstrating a good validity of the questionnaire.There were significant differences in warmth(A),reasoning(B),dominance(E),liveliness(F),rule-consciousness(G),social boldness(H),apprehension(O),openness to change(Q1),self-reliance(Q2),and tension(Q4)between Uygur policemen and policewoman(P<0.05 for all).The levels of A,B,emotional stability(C),H,vigilance(L),abstractedness(M),Q1,Q2,and Q4 were significantly different among the police with different education background(P<0.05 for all).The police engaged in different duty posts showed differences in A,E,F,and M(P<0.05 for all).ConclusionThe 16PF of Uygur version has good reliability,validity and differentiation when applied among Uygur police.The norms of Uighur version 16PF are different among the Uighur police of different gender,education,and duty post.
Physical fitness status and its influence on blood pressure level among adults in Liaoning province
WANG Hong-li, HAN Yan-bai, Shi Juan-juan.et al
2013, 29(10): 1437-1440. doi: 10.11847/zgggws2013-29-10-10
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Objective To investigate physical fitness status and its influence on the blood pressure level among adults in Liaoning province,and to provide information for prevention and control of hypertension.Methods A total of 5 817 adults aged 20-69 years from three settings of the Third China's Nationa1 Physica1 Fitness Surveillance of Liaoning province(Shenyang,Dandong,and Chaoyang city)were selected by using stratified random sampling method.Age groups of adult A(20-39 years),adult B(40-59 years)and elder(60-69 years)were defined.Parameters of anthropometry,physiological function and physical constitution were determined.Results The prevalence of normal blood pressure,high normal blood pressure and hypertension were 58.1%,17.0%,and 24.9% among the adults aged 20-69 years in Liaoning province.The ratio of physical indexes reaching the national fitness standards for the adults with the normal blood pressure,high normal blood pressure,and hypertension were 80.4%,61.2% and 58.3% for the adults of group A,82.2%,76.4%,and 75.3% for the adults of group B,and 91.7%,88.9%,and 84.3% for the elder adults,respectively.For the aduts of group A,the ratio of physical indexes reaching the national fitness standards for adults with the normal blood pressure was significantly higher than that of adults with the high normal blood pressure and hypertension(P<0.01).For the adults in group B and elder group,the ratio of physical indexes reaching the national fitness standards for adults with the normal blood pressure were significantly higher than that of the hypertension(P<0.01).Multiple logistic regression analysis results showed that the risk factors for high normal blood pressure were age,elevated heart rate,overweight and obesity,while the protective factors were female gender and higher step-test index.Risk factors for hypertension were age,higher heart rate,long choice reaction time,larger waist circumference,abdominal obesity,overweight and obesity,while the protective factors were female,higher vital capacity per weight,and larger step-test index.ConclusionAmong adults,physical fitness status affects blood pressure level,and heart rate,body mass index,step-test index,waist circumference,choice reaction time,and vital capacity are main influencing factors of blood pressure.
Status and influencing factors of influenza vaccination among healthcare workers in Ningbo city
WANG Ai-hong, YI Bo, SHEN Tao.et al
2013, 29(10): 1441-1444. doi: 10.11847/zgggws2013-29-10-11
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Objective To determine the coverage of influenza vaccination and its main influencing factors among healthcare workers.Methods We conducted a cross-sectional survey in 1 217 healthcare workers from 30 medical institutions selected with two-stage random sampling.We obtained general information,knowledge about influenza and influenza vaccine,influenza vaccination during the winter season of 2010-2012,and acceptance of influenza vaccination among the healthcare workers,with face-to-face interview.Results Totally 172 healthcare workers were vaccinated during the influenza season of 2010-2012 in the healthcare workers,with a coverage rate of 12.37%.Among the healthcare workers,38.39% reported that they would accept influenza vaccination before the influenza season of 2012 and 62.13%reported that they would accepted influenza vaccination free of charge.The main reasons for the healthcare workers not accepting vaccination were limited efficacy of the vaccine(66.76%),side effects of the vaccine(55.52%),unnecessary vaccination for healthy person(54.15%),inconvenience of annual vaccination(43.20%),and the charge of vaccination(35.30%).Logistic regression analyses showed that knowing effectiveness of influenza vaccine,healthcare workers being the population recommended to be vaccinated,and knowing that the vaccination could be paid by health insurance were significantly associated with higher acceptance of influenza vaccine in the healthcare workers.While knowing that the influenza caccination should be administered annually decreased the perception of influenza vaccination in the healthcare workers.ConclusionThe influenza vaccination coverage and willingness to accept the vaccination were very low among healthcare workers in Ningbo city and lack of confidence to vaccine efficacy and safety,deficiency in awareness of influenza hazard,and the charge of influenza vaccine are main reasons for the healthcare workers without influenza vaccination.
Relationship between lifestyle and sub-health among civil servants in Shenyang
FAN Xin-xin, CHEN Li-ming, XU Jun
2013, 29(10): 1445-1448. doi: 10.11847/zgggws2013-29-10-12
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Objective To examine the status of lifestyle and sub-health and the relationship between lifestyle and sub-health among civil servants in Shenyang city,Liaoning province.Methods From July to September 2010,2 412 civil servants working in public security system,tax business administration,and education system of 5 districts of Shenyang city were selected with multistage stratified cluster random sampling and surveyed with a lifestyle questionnaire and Sub-Health Measurement Scale Version 1.0(SHMS V1.0).Results The prevalence rate of sub-health for the civil servants in tax system was the highest(58.11%),followed by that of civil servants in public security system(50.95%).Civil servants in public security system had lower scores than the civil servants in other 3 systems in organ function,psychological symptoms,cognitive function score,psychological sub-health,and overall sub-health(62.64±16.976,66.13±18.141,57.13±17.860,63.47±15.345,and 63.60±13.283)(P<0.05 for all).The civil servants in education system had lower scores than those of the civil servants in other 3 systems in physical symptoms,physical excercise function,energy,positive emotions,social adaptation,social resources,support,physical sub-health,and social sub-health(52.55±16.774,70.24±24.609,54.56±28.497,51.66±32.282,56.68±28.649,54.10±21.259,63.57±13.471,and 59.27±19.198)(P<0.05 for all).The results of multiple linear regression showed that smoking,alcohol drinking,skipping breakfast,lack of sleep,lack of exercise,commuting using different means of transportation,and social activities were major lifestyle factors affecting sub-health among the civil servants(P<0.05 for all).ConclusionUnhealthy lifestyle is the main factor related to sub-health among civil servants in Shenyang city.Education and intervention measures should be strengthened to improve the health of the civil servants.
2013, 29(10): 1448-1449. doi: 10.11847/zgggws2013-29-10-13
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Determination of quinolones antibiotics residues in animal edible products
CAO Yi-yao, XU Chong-de, LIU Ping.et al
2013, 29(10): 1450-1452. doi: 10.11847/zgggws2013-29-10-14
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Objective To establish an accurate,rapid,and sensitive method for simultaneous detection of three quinolones(QNs) including ofloxacin(OFL),ciprofloxacin(CIP),and enrofloxacin(ENR)residues in animal edible products.Methods The residues in the samples were extracted by acidified acetonitrile(ACN)and ultrasonic wave device,and then the impurities were removed by liquid-liquid extraction(LLE)with hexane.After concentrated,the residues were dissolved by ACN-water(8:2)and then determined with high-performance liquid chromatograply-ultraviolate-visible detector(HPLC-UVD).The mobile phase was ACN and sodium dihydrogen phosphate solution(0.01mol/L,pH=4.0);gradient elution was used and the detection wavelength was 279 nm.Results OFL,CIP and ENR were seperated succssfully and the chromatographic peaks were sharp and symmetrical.The correlation coefficients were all above 0.999 6.The relative standard deviations of OFL,CIP,and ENR were all below 5%,with good reproducibilities.The recovery rates were all more than 85%.The limit of determination(LOD)of OFL,CIP,and ENR was 2.7×10-3 μg/ml,1.4×10-3 μg/ml,and 6.5×10-4 μg/ml,respectively.ConclusionThe method established is suitable for rapid,accurate,and simultaneous detection of OFL,CIP,and ENR in animal edible prodults.
Effects of arsenite on D-serine released from astrocytes and its related mechanism
WANG Yan, JIN Ya-ping, ZHENG Lin-lin.et al
2013, 29(10): 1452-1455. doi: 10.11847/zgggws2013-29-10-15
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Objective To investigate the intellectual impairment induced by arsenite through studying the effects of arsenite on D-serine released from astrocytes and its related mechanism.Methods The primary cultured astrocytes were divided into four groups randomly,in which astrocytes were exposed to 0,2.5,5 or 10 μmol/L arsenite for 24 hours.The level of D-serine was measured with high performance liquid chromatography(HPLC);the protein expression of serine racemase(SR)was measured with western blot;the intracellular free Ca2+ concentration([Ca2+]i)in astrocytes was measured with fluorescence dual wavelength spectrophotometer.Results Compared with those in control group,the levels of D-serine released from astrocytes(21.580±1.313,21.936±1.539 and 23.401±1.648 μmol/L)and the protein expression of SR(1.327±0.122,1.397±0.105,and 1.403±0.104)increased significantly in groups treated with arsenite;and [Ca2+]i(0.26±0.01 μmol/L)in the group treated with 10 μmol/L arsenite increased significantly.Conclusion Arsenite could increase the level of D-serine released from astrocytes and its mechanism could be related with the increasing protein expression of SR and the elevated [Ca2+]i in astroytes induced by arsenite.
Effects of hydroquinone on LKB1 expression in BM-HSC and YS-HSC in mice
GUO Li-qiao, LI Zhen, ZHU Jie.et al
2013, 29(10): 1455-1457. doi: 10.11847/zgggws2013-29-10-16
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Objective To explore the effects of hydroquinone(HQ)on the protein expression of liver kinase B1(LKB1)in bone marrow hematopoietic stem cells(BM-HSC)and embryonic yolk sac hematopoietic stem cells(YS-HSC)in mice.Methods BM-HSC and YS-HSC were enriched by magnetic-activated cell sorting(MACS).The BM-HSC and YS-HSC were cultured in suspension of stem span serum-free expansion medium containing 0,1.25,2.5,5.0 and 10 μmol/L hydroquinone.Cell viability,mRNA and protein expression of LKB1,intracellular reactive oxygen species(ROS),and apoptosis of BM-HSC and YS-HSC were determined.Results The relative expression of LKB1 mRNA for the HQ dose of 0,1.25,2.5,5,and 10 μmol/L were 1.00,1.27±0.057,1.18±0.021,0.89±0.009,and 0.68±0.006 in BM-HSC and 1.00,1.33±0.024,0.96±0.017,0.7±0.008,and 0.54±0.022 in YS-HSC.The expression of LKB1 mRNA in BM-HSC and YS-HSC were significantly different among different HQ dose groups (P<0.05).The results of protein and mRNA expression of LKB1 were consistent in different HQ dose groups.The results of cell apoptosis were consistent with the expression of LKB1.ConclusionHQ could decrease mRNA and protein expression of LKB1 in BM-HSC and YS-HSC with a dose-effect response,and HQ induced-oxidative stress is correlated with the activity of LKB1.
Inhibitive effect of juglone on prostate cancer PC-3 cells
FANG Fang, WANG Li-guo, ZHANG Wei.et al
2013, 29(10): 1458-1460. doi: 10.11847/zgggws2013-29-10-17
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Objective To explore inhibitive effect of juglone on prostate cancer PC-3 cells.Methods The 3-(4,5 dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide(MTT)assay was used to determine the growth of PC-3 cells treated with different concentrations of juglone.The induction of apoptosis was detected by flow cytometry with annexin V-FITC/PI staining.Western blot was used to detect the expression of apoptosis-associated protein of B-cell lymphoma(Bcl-2)and Bcl-2-associated X protein(Bax).Results Juglone could significantly inhibit the growth of PC-3 cells in dose-dependent manner with the inhibition ratios of 20.6%,39.7%,57.3%,and 66.2%,respectively.Flow cytometry detection showed that the early and late apoptosis rates of PC-3 cells treated with juglone of 25,50,and 100 μmol/L were 7.37% and 2.07%,11.03% and 5.8%,and 18.62% and 8.54%,respectively,and higher than those of the control group(P<0.05).High dose of juglone(≥50 μmol/L)could reduce the expression of apoptosis-regulated protein Bcl-2 and increase the expression of apoptosis-regulated protein Bax(P<0.05).ConclusionJuglone can suppress the growth of PC-3 prostate cancer cells.
Effects of adenosine on lipopolysaccharide induced myocardial cell hypertrophy in neonatal rats
YANG Li-ru, YANG Yu-hong, LIANG Ling-jun.et al
2013, 29(10): 1460-1462. doi: 10.11847/zgggws2013-29-10-18
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Objective To investigate the effects and mechanism of adenosine(ADO)on lipopolysaccharide(LPS)-induced neonatal rat cardiomyocyte hypertrophy.Methods The hypertrophy of primary cardiac cells of neonatal rat was induced by 1 mg/L LPS and the effect of different concentrations of adenosine on cardiac hypertrophy was observed.The size of cardiomyocytes was measured wtih a computer photograph analysis system and the expression of atrial natriuretic peptide mRNA was determined by reverse transcription PCR.Toll like receptor 4(TLR4)and tumor necrosis factor-α(TNF-α)were determined with western blot and enzyme-linked immunosorbent assay.Results Adenosine inhibited lipopolysaccharide-induced cardiac hypertrophy,with the decreased volume of 15.6%,27.1%,and 32.8% for low,moderate,and high ADO treament compared with that of model group(P<0.05 for all).The expression of atrial natriuretic peptide mRNA also decreased(P<0.01).ADO treatment abolished the inflammatory response induced by LPS,which was partially via attenuating TLR 4 signal pathway(P<0.05).The TNF-α decreased obviously by 56.3%,67.8%,and 72.9% at ADO doses of 0.25,1.00,and 4.00 mg/L(P<0.01 for all).ConclusionAdenosine has a protective effect on LPS-induced cardiac hypertrophy.The mechanism may be related to the inhibition of TLR 4.
Antitumor and immunomodulatory function of Lycium barbarum polysaccharides in combination with 5-fluorouracil
LI Xiao-bing, XIE Zhong-li, ZHU Yan-qin.et al
2013, 29(10): 1463-1465. doi: 10.11847/zgggws2013-29-10-19
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Objective To observe the effects and mechanisms of Lycium barbarum polysaccharide(LBP)alone and combination with 5-fluorouracil (5-FU) on S180 tumor bearing mice.Methods Mouse S180 cells were subcutaneously injected into right axillary region of the mice.Eighty mice were randomly assigned into control group,5-FU group,LBP group,and LBP combined with 5-FU(LBP + 5-FU)group.Tumor weight and tumor control rate were detected after the experiment.Lymphproliferation response was detected with methyl thiazolyl tetrazolium(MTT)method.Cytotoxicity of nature killer(NK)cells to tumor cells was measured by lactate dehydrogenase(LDH).Macrophage phagocytosis was detected with neutral red experiment;nitrogen oxide(NO)production was detected by Griess and tumor necrosis factor-alpha(TNF-α)in peripheral blood was inspected by enzyme-linked immunosorbent asay(ELISA).Results LBP inhibited S180 tumor growth.The tumor control rate was 38.7% in high dose LBP group.Lymphoproliferation response of midium or high dose of LBP alone and combination with 5-FU group increased significantly compared with 5-FU group(P<0.01).Compared with the control group,cytotoxicity of NK cells to tumor cell in low,midium,and high dose LBP group increased significantly,with the proportions of 46±6%,52±11%,and 63±10%,respectively.Compared with 5-FU group,the phagocytosis of macrophage,nitric oxide production and level of TNF-α in serum in high dose LBP combination with 5-FU group increased significantly(P<0.01).ConclusionThese results suggest that LBP combination with 5-FU decrease the immune system damage induced by 5-FU.LBP might be a potential adjuvant for chemotherapeutic drugs.
Sulforaphane prevents palmitic acid-induced mitochondrial impairments of cardiomyocyte in vitro
HU Li-zhen, LI Ya-jie, XUE Hong-feng.et al
2013, 29(10): 1466-1469. doi: 10.11847/zgggws2013-29-10-20
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Objective To investigate the protective effect of sulforaphane(SFN)on H9c2 myocardial cells treated with high fat.Methods H9c2 cells were cultured in vitro,and were treated with 350 μmol/L palmitic acid for 24 hours to set up cellinjury model.The model cells were pretreated with different dose of SFN(1,5,7.5,and 10 μmoll/L)for 24 hours and was pretreated by 5 μmol/L SFN for different time(12,24,36,and 48 hours),then the cellular viabilities were detected with trypan blue staining.Fluorescent probes were used to determinate reactive oxygen species(ROS)and mitochondrial membrane potential(MMP).Thiazolyl blue staining was used to detect mitochondrial succinic dehydrogenase(SDH)activity.Mitochondrial morphous was observed with electron microscope.The mRNA expression levels of nuclear respiratory factor 1 and 2(NRF1,NRF2)were detected with reverse transcription polymerase chain reaction(RT-PCR).Results Compared to the control group,the cellular viability of cellinjury model group(38.04±12.69%)decreased(P<0.05),while SFN(5 μmol/L,24 hours)of pretreated group(69.37±6.35%)wase significantly increased(P<0.05).The ROS production of SFN group(86.27±1.44%)was significantly decreased compared to that of cellinjury model group(124.72±11.54 %)(P<0.05).The MMP,SDH activity(37.88±6.92 %,66.59±6.92%)and the mRNA expression levels of NRF1and NRF2(61.72±11.58% and 131.16±14.52%)of SFN group were significantly increased compared to cellinjury model group(P<0.05).SFN pretreatment alleviated mitochondrial pyknosis and mitochondrial quantity reduction.ConclusionSulforaphane can reduce mitochondrial damage induced by high fat,therefore protect myocardial cells exposed to a high-fat environment.
Establishment and reliability and validity evaluation of a self-rated psychological sub-health questionnaire
WEI Bo, TANG Zheng-hua, TANG Shuai.et al
2013, 29(10): 1469-1472. doi: 10.11847/zgggws2013-29-10-21
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Objective To develop a self-rated psychological sub-health questionnaire for medical students and to evaluate its validity and reliability.Methods Based on the results of clinical interview,case study,and literature review,we worked out a self-rated psychological sub-health questionnaire and 499 medical students were asked to complete the questionnaire.The data were analyzed with project analysis,exploratory factor analysis,and reliability and validity tests.Results The questionnaire was finally confirmed as a list of 35 items on 6 dimensions,including emotional response,learning difficulties,being world-weary or studying-weary,self cognition,somatization,and abnormal consciousness,with a cumulative contribution rate of 45.653%. The Cronbach α coefficients for the total score and 6 dimensions were 0.877 and 0.850,0.732,0.690,0.510,0.642,and 0.632,respectively.The related coefficients of 6 factors and the whole questionnaire were 0.834,0.664,0.651,0.438,0.645,and 0.607,respectively.ConclusionThe questionnaire has a good reliability and validity,and could be used as screening tool for assessment of psychological sub-health among medical students.
Reliability and validity of Obsessive Belief Questionnaire-44,Chinese Version
WANG Yu-ping, WANG Qin, LEI Hui.et al
2013, 29(10): 1473-1476. doi: 10.11847/zgggws2013-29-10-22
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Objective To examine the reliability and validity of Obsessive Belief Questionnaire-44,Chinese Version(OBQ-44).Methods The OBQ-44,Yele-Brown Obsessive Compulsive Scale(Y-BOCS)and Obsessive-Compulsive Iventory-Revised(OCI-R)were administered to 76 obsessive-compulsive disorders(OCD)patients and 841 adolescents.The Cronbach's alpha coefficients,mean inter-item correlations,test-retest reliability,factorial validity and criterion validity were calculated to assess the reliability and validity of OBQ-44.Results The Cronbach's α coefficient of the OBQ-44 in two groups were over 0.95,and the Cronbach's α coefficients of the three factors were over 0.90.Test-retest reliability of OBQ-44 and its three factors were over 0.50.Indices of confirmatory factor analysis were cofirmatory fit index(CFI)(0.91),Tucker-Lewin index(TLI)(0.90),χ2/df(3.75) and root mean square error of approximation(RSMEA)(0.06),which supported the original OBQ-44 structural hypothesis of three factors model.There ware significant positive correlations among OBQ-44 and its three factors with Y-BOCS and OCI-R.ConclusionThe Obsessive Belief Questionnaire-44-Chinese Version is of good reliability and validity,which could serves as an excellent measuring tool for assessing obsessive beliefs in Chinese population.
Relationship between medication adherence of warfarin and social support in patients with mechanical heart-valve replacement
ZHOU Ting-ting, SI Zai-xia, ZHOU Min.et al
2013, 29(10): 1476-1478. doi: 10.11847/zgggws2013-29-10-23
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Objective To investigate the present situation of and relationship between medication adherence of warfarin and social support in patients with mechanical heart-valve replacement,and to provide evidence for improving medication adherence of the patients.Methods The social support scale and the modified Chinese Version Morisky Medication Adherence Scale(MMAS-8)were used and the information on 156 discharged patients with mechanical heart-valve replacement were collected through telephone interviews.Results The average score of medication adherence of warfarin was 7.25±0.93,and 88.4% of the patients had an upper-medium medication adherence.The total score of social support for the patients was 47.07±6.23.The medication adherence was positively correlated with the scores of social support and it's three dimensions among the patients(P<0.05).Multiple stepwise regression analyses showed that social support,age,as well as educational level were influencing factors of medication adherence of warfarin,and the most predominant factor for medication adherence was social support.ConclusionThe medication adherence of warfarin was influenced by social support in patients with mechanical heart-velve replacement,and the adherence could be improved by the medical staff through helping the patients to get more familial and social support.
Application of decision tree combined with biomarkers in auxiliary diagnosis of lung cancer
WEI Xiao-ling, TAN Shan-juan, HE Qi-dong.et al
2013, 29(10): 1479-1482. doi: 10.11847/zgggws2013-29-10-24
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Objective To diagnose lung cancer by detections of p16,RASSF1A,fragile histidine traid(FHIT)genes promoter methylation status,and relative telomere length in peripheral blood DNA and to identify the significances of discrimination analysis and decision tree for auxiliury diagnosis of lung cancer.Methods The levels of p16,RASSF1A,FHIT genes promoter methylation,and relative telomere length in peripheral blood DNA of 200 healthy individuals and 200 patients with lung cancer were measured by SYBR green-based quantitative methylation-specific PCR and quantitative PCR,respectively,and then discrimination analysis and decision tree models were developed.Results The levels(95% confidence interval)of p16,RASSF1A,and FHIT genes promoter methylation of the lung cancer patients and healthy individuals were 0.59(0.16-4.50)and 0.36(0.06-4.00)(P=0.008),27.62(9.09-52.86)and 17.17(3.86-50.87)(P=0.038),and 3.33(1.86-6.40)and 2.85(1.39-5.44)(P=0.002),respectively,and the relative telomere lengths were 0.93±0.32 and 1.16±0.57(P<0.001).There were statistically significant differences in the four biomarkers between the two groups.The accuracies of discrimination analysis and decision tree models were 64% and 83%,respectively and the areas under receiver operating curve were 0.640 and 0.830,with statistically significant differences between the two groups(P<0.05 for all).ConclusionThe efficacy of decision tree model established with data mining tool is better than that of discrimination analysis in auxiliary diagnose of lung cancer auxiliary.
Effects of different dose rosuvastatin on expressions of matrix MMP-2 and MMP-9 in unstable plaque in rabbits
PANG Xiao-ling, ZHANG Hong-ying, ZHOU Hong.et al
2013, 29(10): 1482-1484. doi: 10.11847/zgggws2013-29-10-25
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Objective To explore effects of rosuvastain on expressions of matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-9(MMP-9)in vulnerable plaque in rabbits.Methods Fourty healthy male New Zealand white rabbits were randomly divided into four groups:control group(n=10),vulnerable plaque group(n=10),low dose rosuvastatin group(n=10,1 mg/kg/d)and high dose rosuvastatin group(n=10,2 mg/kg/d).Total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),and triglyceride(TG)were detected before and 1 month after the treatment,respectively.At the end of experiment,all rabbits were sacrificed and expressions of MMP-2 and MMP-9 were determined with immunohistochemical assays.Results Compared to the control group,the concentrations of TC,TG,and LDL-C significantly decreased in rosuvastain treatment groups(11.93±0.35 and 13.73±0.35 mmol/L,6.24±0.37 and 7.53±0.36 mmol/L,and 4.28±0.23 and 4.83±0.25 mmol/L for high dose and low dose group);the concentration of HDL-C increased significantly(1.93±0.24 for high dose group and 1.62±0.22 mmol/L for low dose group)(P<0.05 for all).The results of immunohistochemical assays showed that the expressions of MMP-2 and MMP-9 in unstable plague of abdominal aorta were significantly decreased in high and low dose rosuvastatin treatment groups(P<0.05 for all)compared to that of control group.ConclusionRosuvastatin improves blood lipid levels and reduces expressions of MMP-2 and MMPv9 which might stabilize the atherosclerotic plaques in rabbits.
Prevalence of self-medication with antibiotics in kindergarten children of Guangzhou city
YAO Zhen-jiang, ZHOU Jun-li, LI Ying.et al
2013, 29(10): 1485-1487. doi: 10.11847/zgggws2013-29-10-26
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Objective To assess the prevalence and determinants of self-medication with antibiotics among children in Guangzhou city,Guangdong province.Methods Multi-stage sampling method was used to select 1 295 kindergarten children.A self-administered questionnaire survey was used to investigate the prevalence of self-medication with antibiotics in the children and its influence factors.Results Totally 80.15% of families keept antibiotic at home,63.47% of the children had been given an antibiotic in the past 12 months by their guardian,31.51% of children were given amoxicillin and 25.56% given cefalexin.The parents'educational level and antibiotics kept at home were the main determinants of self-medication with antibiotics in the children.With the ascending of the parents' educational level,the probability of self-medication with antibiotics in the children decreased.Compared to the parents with education of master degree,the odds ratio(OR)value of self-medication for their child was 5.042(95% confidence interval[95%CI]:1.495-17.002)for the parents with primary school education,2.358(95%CI 1.150-4.838)for the parents with junior high school education,and 2.104(95%CI 1.106-4.003)for the parents with high school education,respectively.The OR value of parents implemented self-medication with antibiotics for the children in family keeping antibiotics at home was 4.792(95%CI 3.541-6.485)compared to the children with family not keeping antibotics at home.ConclusionThe prevalence of self-medication with antibiotics for kindergarten children is higher in Guangzhou.The effective education on rational use of antibiotic for the kindergarten children's parents is urgently necessary.
Burden of cardiovascular diseases in residents of Shiyan city,2007-2009
LIU Rui, ZHOU Shang-cheng, LIU Ying.et al
2013, 29(10): 1488-1491. doi: 10.11847/zgggws2013-29-10-27
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Objective To investigate the mortality and burden of cardiovascular diseases in residents of Shiyan city.Methods The data on mortality of cardiovascular diseases among residents of Shiyan city from 2007 to 2009 were collected and analyzed.The mortality rate,age-adjusted mortality rate,and disability-adjusted life years(DALYs)were calculated.Results From 2007 to 2009,the crude death rate and age-adjusted mortality of cardiovascular diseases were 201.9/100 000 and 173.9/100 000,respectively.The age-adjusted mortality of male and female were 211.9/100 000 and 137.6/100 000,respectively.Among the males,the intensity of DALYs was 31.7,whereas that among the females was 20.9.The males had greater DALYs per thousand population than the females.The people aged above 60 years had the highest death rate and intensity of DALYs.Cerebrovascular diseases,ischaemic heart disease,and hypertension were three leading causes of the burden of cardiovascular diseases.ConclusionThe prevention and treatment of cardiovascular diseases for males and people aged ≥ 60 years should be enhanced in Shiyan city.
Reproductive health status and related factors among female college students with different specialty
ZHANG Feng-yun, RAO Yan, SHENG Lei.et al
2013, 29(10): 1492-1494. doi: 10.11847/zgggws2013-29-10-28
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Objective To explore reproductive health status and related factors among female college students with different specialty and to provide evidence for making intervention measures.Methods With stratified random cluster sampling,1 738 female college students from 4 colleges at Hangzhou university-town were selected for a questionnaire survey.Data on the status of reproductive health as well as on the related factors were collected.Results The average age of the female college students was 20.87±1.38 years.Among the students,the average age at menarche was 14.11±1.27 years and the average length of menstrual cycle was 29.75±4.30 days.There were 31.24% of the respondents reporting irregular menstrual cycles,87.17% reporting reproductive health problems and 26.58% of them sought medical advice because of reproductive health problems in the previous one year.The situation of non-medical students was worse than that of medical students.The main reproductive health problems included menstrual disorder(54.95%),dysmenorrhea(49.19%),lumbago(25.26%),breast pain(15.82%),and abnormal leucorrhea(15.13%).Only 68.53% of respondents cleaned vulva every day,and the rates of sexual intercourse and masturbation were 7.25% and 5.24%.Cleaning vulva correctly(odds ratio[OR]=0.527)and sexual intercourse(OR=2.15)influenced the status of reproductive health among the students.ConclusionThe status of reproductive health among female college students is not good,which is associated with many factors.
Clinical characteristics and epidemiology of novel bunyavirus human infection cases in Dandong city,2010-2012
ZHANG Yong-gang, CUI Rong-min, YU Dan-mei.et al
2013, 29(10): 1495-1498. doi: 10.11847/zgggws2013-29-10-29
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Objective To analyze the clinical features and epidemiological characteristics of human infection of novel bunyavirus and to provide evidences for making prevention and control measures.Methods Case study was conducted with uniform diagnostic criteria and questionnaire survey.Results From 2010 to 2012,a total of 52 cases of novel bunyavirus infection were confirmed in Dandong city,with an average annual incidence rate of 2.16/100 000 and a fatality rate of 7.69%.The main clinical manifestations of the cases were fever(100%),body pain(82.7%),headache(75%),fatigue(71.2%),and nausea(76.9%).The blood examinations showed a reduced platelet counts(98.1%)and a decreased white blood cell count(92.3%).Of the cases 71.2% showed symptoms of a cold.A great number of cases came from the mountainous and hilly areas and the majority of the cases were male,elderly persons,farmers,with the onset time from June to October.A clear history of tick bite before the onset was reported by 48.1% of the cases.A secondary case was the sister of a confirmed male case and had a hsitory of blood contact.ConclusionThe initial clinical symptoms of novel bunyarirus infection are cold and atypical symptoms and the incidence of the infection presents obvious geographical characteristics,with sporadic cases.Animal and tick vector play an important role in human bunyavirus infection but human to human transmission of the virus could not be ruled out.
Genetic polymorphisms of cytochrome P450 and glutathione S-transferase in relation to human esophageal carcinoma
ZHANG Lin, MA Wei, LI Yun.et al
2013, 29(10): 1499-1501. doi: 10.11847/zgggws2013-29-10-30
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Objective To explore genetic polymorphisms of cytochrome P4501A1(CYP1A1)and 2EI(CYP2EI),glutathione S-transferase M1(GSTM1)and(GATT1)in relation to human esophageal carcinoma.Methods The genetic polymorphisms of CYP1A1,CYP2E1,GSTM1 and GATT1 in 138 esophageal carcinoma patients and 170 normal controls were detected.Results The genetic polymorphisms of CYP1A1 and GSTT1 were not related to the risk of esophageal carcinoma.The genetic polymorphisms of CYP2E1 and GSTM1 were related to the risk of esophageal carcinoma.The risk of esophageal carcinoma in people with C1 allele was 2.207 times of the people with C2 allele.The risk of esophageal carcinoma in people with C1/C1 allele was 2.256 times of the people with other genotypes.The risk of esophageal carcinoma in people with GSTM1 null was 1.775 times of the people with other genotypes.ConclusionThe genetic polymorphisms of CYP2E1 and GSTM1 are related to human esophageal carcinoma.
Influence of obesity and diabetes on ischemic stroke
MA Cui, LI Yan, LI Xi-dong.et al
2013, 29(10): 1502-1505. doi: 10.11847/zgggws2013-29-10-31
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Objective To examine the association between different indicators of adiposity(body mass index [BMI] and wais-tto-hip ratio[WHR]),diabetes and the risk of ischemic stroke(IS).Methods A hospital-based case-control study was conducted.Cases(n=311)were patients ≥25 years old with ischemic stroke,who were admitted to Department of Neurology of First Affiliated Hospital and Third Affiliated Hospital of Liaoning Medical University,and Jinzhou Central Hospital between April 2011 to September 2012.Frequency-matched controls(n=311)were patients who had been admitted to the same hospital for diseases not related to stroke.All subjects were surveyed using a structured interviewer-administrated questionnaire and laboratory examinations.Results Multiple logistic regression analyses showed that compared to the controls with normal BMI,overweight and obesity were associated with a significantly increased risk for IS(odds ratio [OR]=1.571,95% confidence interval[95%CI]:1.0153-2.582,P=0.034;OR=1.775,95%CI:1.101-2.785,P=0.002,respectively).Compared to the controls in the lowest quartile,after adjusting for multiple potential confounders,the risk for IS in the highest quartile of WHR was increased by 36.0%(OR=1.360,95%CI:1.175-1.855,P=0.009).Compared to the controls in the lowest quartile,the OR for third and the highest quartile of fasting plasma glucose(FPG)were 1.566(95%CI:1.023-2.314,P=0.029)and 1.791(95%CI:1.159-2.725,P=0.018).Further multivariate logistic regression models showed that participants with diabetes had 2 times risk of IS as did the nondiabetic(OR=2.013,95%CI:1.245-2.987,P<0.001).Compared to the nondiabetic,the risk of IS in the participants with diabetes history <10 years and 10 to 20 years significantly increased(OR=2.264,95%CI:1.458-3.532,P=0.003;OR=2.317,95%CI:1.120-5.876,P=0.005,respectively).Conclusion Higher BMI,WHR,and diabetes were positively related to IS.Therefore,keeping normal weight and blood glucose may protect against IS.
Epidemiological characteristics and disease burden of road traffic injuries in Nanning city
HE Hui-min, YANG Li, HUANG Kai-yong
2013, 29(10): 1506-1508. doi: 10.11847/zgggws2013-29-10-32
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Objective To analyse epidemiological characteristics and disease burden of road traffic injuries(RTI)in Nanning city from 2000 to 2009,and to provide scientific basis for prevention and control of RTI.Methods The data on RTI in Nanning city were collected from Guangxi Traffic Police Corps and Guangxi Statistics Bureau,and then the epidemiological characteristics,casualties and disease burden of RTI were analyzed.Results The number of RTI was steady from 2000 to 2003,but increased suddenly in 2004(1 038)and went up to the peak in 2005 (1 532).Then the number showed a downward trend from 2005 to 2009.Qingxiu district,Xixiangtang district and Xingning district showed high incidents of RTI,with the total RTI numbers of 1 886,1 578,and 1 432.The male-female ratio of the injuriy and death of RTI was 2.72:1.The deaths occured mainly in the people aged 16 to 50 years,with a number of 1 173,accounting for 71.83% of total deaths in the city.The casualties were mainly caused by incidents of motorcycles,walking,bike,and by car.The main reason of RTI was violating traffic regulations,accounting for 19.7% of all RTI.Years of life lost(YLL)due to RTI in Nanning city from 2000 to 2009 was 39 987.56 person-year,with on economic loss of 260 million RMB yuan.ConclusionThe number of RTI showed a downward trend from 2000 to 2009.But the economic loss due to RTI was serious during the period of 10 years in Nanning city.
Change trends in health behaviors among residents in Liaoning province,1991-2006
LUAN De-chun, LI Sui-jing, LI Hui.et al
2013, 29(10): 1509-1511. doi: 10.11847/zgggws2013-29-10-33
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Objective To analyze the change trends of health behaviors among residents in Liaoning province from 1991-2006.Methods Based on the data from China Health and Nutrition Survey in Liaoning Province(1991,1993,2000,2004 and 2006),change trends in health behaviors,such as smoking,alcohol drinking,exercise and sedentary lifestyle were analyzed.Results From 1991 to 2006,the prevalence of smoking among the adults aged 18 years and older decreased from 35.5% to 29.3%(χ2=8.37,P=0.0431),and the prevalence decreased in the males from 66.8% to 53.0%(χ2=19.14,P=0.021 0),but no significant change was found in the females.However,the amount of smoking in the smokers increased from 13.1 to 16.2 cigarettes per day(F=22.65,P<0.000 1).The prevalence of alcohol consumption in men was also decreased from 70.5% to 59.8% and from 14.7% to 7.5% in women from 1991 to 2006(χ2=12.06,P=0.000 5;χ2=14.15,P=0.000 1).Compared with 2004,the consumption of soft drinks increased,the consumption of fruit juice beverage decreased among children and adolescents in 2006,and the percentage of children and adolescents drinking beverage everyday increased from 9.8% to 11.6%(χ2=5.31,P<0.000 1).From 2000 to 2006,the prevalence of regular exercise in adults increased from 6.3% to 16.5%,but decreased from 46.5% to 32.1% in children and adolescents(χ2=51.71,P<0.000 1;χ2=6.53,P=0.010 6).In the adults,children,and adolescents,the time of computer use was increased in 2006 compared with that in 2004.The time of computer use increased from 13.0 to 20.5 hours per week in adults and increased from 9.5 to 13.0 hours per week in children and adolescents(F=5.49,P=0.020 6;F=17.51,P<0.000 1).ConclusionThe prevalences of smoking and alcohol drinking decreased in residents of Liaoning province,but attention should be paid to the increases of soft drinks consumption and of sedentary time.
Knowledge,attitude and practice about food safety among college students
XU Shang-zhi, ZHANG Dong- xing, MA Dan.et al
2013, 29(10): 1512-1514. doi: 10.11847/zgggws2013-29-10-34
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Objective To investigate the knowledge,attitude and practice(KAP) about food safety and its impact factors among college students in Shihezi University,and to provide reference for food safety education. Methods A total of 1 492 students were randomly selected form 17 colleges and surveyed with a questionnaire.Results The average score for food safety was 5.65±2.00 among the students.The average score of the medical students(5.77±1.87)was higher than that of the non-medical students(5.46±2.17),with a significant difference (Z=-2.51,P<0.05);the score of the female students (5.83±1.88)was significantly higher than that of the male students (5.39±2.13)(Z=-4.00,P<0.05);the score of Han students(5.79±1.97)was significantly higher than that of the minority students(5.01±1.99),(Z=-5.38,P<0.05).The students having taken food safety-related courses had a significantly higher score(5.98±2.00)than the students not taking the course(5.51±1.99)(Z=-2.67,P<0.05).Television and internet were the main ways for the students to access the information and knowledge about food safety.ConclusionThe knowledge about food safety is not high among college students.The specification,gender,ethnicity,and whether taking nutrition or food safety-related courses are the main influencing factors of KAP about food safety among college students.
Association of laboratory equipment collocation with capability of scientific research,education and disease control
LU Liang-ping, ZHENG Yu-hong, LUO Cheng-wang.et al
2013, 29(10): 1515-1517. doi: 10.11847/zgggws2013-29-10-35
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Objective To examine the association of laboratory equipment collocation with the capability of scientific research,education and disease control and to provide scientific evidence for reasonable laboratory equipment collocation.Methods Description method was used to evaluate the change of laboratory equipment from 2001 to 2011 in an institute for disease control and prevention.Linear correlation was used to analyse the association between laboratory equipment collocation and the capability of scientific research and education.The capability of disease control was denoted by the time of laboratory test and participating in public health emergency management.Results The laboratory equipment was increased greatly from 2001 to 2011 in the institute mainly in the year of 2004,2008 and 2010.There were significant positive correlations between the laboratory equipment collocation and the scientific capability research and education,with the coefficients of correlation for the numbers of research projects,papers published and the number of educatee of 0.795,0.902,and 0.707.The time of laboratory test was shortened and the capability of disease control was improved owing to the increase of the laboratory equipments.ConclusionThe improvement of laboratory equipment accelerated the capability of scientific research,education and disease control greately in the institute.Advanced laboratory equipments are needed for capability development of the institute.
Personality trait and its effect on mental health among soldires of combat troops
ZHANG Jing-lan, DAI Qing-qing, LI Zi-jian.et al
2013, 29(10): 1518-1520. doi: 10.11847/zgggws2013-29-10-36
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Objective To investigate the personality trait and its effect on mental health among the soldires in combat troops.Methods A total of 1 435 soldiers were enrolled in this study.Symptom Checklist-90(SCL-90)and Eysenck Personality Questionnaire(EPQ)were used in the survey.Results The total score of SCL-90 in the soldiers was 123.17±37.90,with a positive rate of 26.2%.The score was 8.13±2.33 for psychoticism(P),10.76±0.34 for extroversion(E),10.28±4.47 for neuroticism(N),and 10.19±2.18 for concealment tendency(L),respectively.The score of P in the soldires showed a positive skew distribution and the N score and L score a negative skew distribution.The score of E showed a normal distribution.The mean of P was significantly higher than the norm of Chinese people and Chinese soldiers(P<0.001 for all).The mean of L was significantly lower than the norm of Chinese people and Chinese soldiers(P<0.001 for all).The mean of E was significantly lower than the norm of Chinese soldiers but significantly higher than that of Chinese norm(P<0.001).The mean of N was significantly lower than the norm of Chinese soldiers(P<0.05),but was not significantly different from the norm of Chinese people.The scores of P and N in SCL-90 were negatively correlated with each SCL-90 dimension score and total score(P<0.001).The results of regression analyses showed that psychoticism and neuroticism were the important personality trait influencing the mental health among the soldiers(F=123.46,P<0.01).ConclusionPersonality trait affect mental health of the soldiers in combat troops significantly.Trainning and developing sound personality is a effective way to maintain mental health.
Prevalence of artificial abortion and its influential factors among rural married reproductive women
XIAO Yong-hong, GAO Ya-ping, HU Zhen-hua.et al
2013, 29(10): 1521-1523. doi: 10.11847/zgggws2013-29-10-37
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Objective To explore current situation of artificial abortion and its influential factors among rural married reproductive women for making specific intervention strategies.Methods Using multi-stage cluster sampling method,920 married reproductive women under the age of 49 years were recruited in rural areas of Hebei province and their artificial abortion status was investigated with a self-made questionnaire by face-to-face interview.Logistic regression model was used for multiple factor analysis.Results There were 36.3%(334/920)of the women reporting at least one artificial abortion,with 14.9% reporting 2 or more artificial abortions.The main reasons for the artificial abortion were violating family planning policy and contraceptive failure causing accidental pregnancy(76%)in total.The main places of the abortion operations were township hospital(32.6%),general hospital at or above county level(19.2%),maternal and child health hospital(16.5%),and family planning service centre(15.3%).In addition,10.8% of the women with artificial abortion chose village clinics and 5.7% chose private clinics.There were about 95.0% of the women surveyed considering adverse effects of artificial abortion on women's health.Multivariate logistic regression analyses showed that the women with high education level,high annual family income,few pregnant times,and contraceptive measure had low rate of artificial abortion.ConclusionEducation on family planning policy,contraception knowledge,and contraceptive measures need to be promoted to reduce abortion rate among rural married reproductive women.
Evaluation on reliability and validity of 14-Item Resilience Scale
NI Qian-yu, TIAN Jun
2013, 29(10): 1524-1527. doi: 10.11847/zgggws2013-29-10-38
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Objective To evaluate the reliability and validity of the 14-Item Resilience Scale(RS-14)Chinese Version for further clinical resilience assessment.Methods The reliability and validity of the the RS-14 were tested in 446 medical practitioners in Fujian province and residents from Junmen community in Fuzhou city.Results Factor analysis indicated that the Chinese version RS-14 was composed of two factors:personal ability and positive perception,which could explain 60.755 percent of the total variance. The correlation coefficient between RS-14 and mental health subscale in the Medical Ooutcomes Study 36-Item Short Form Health Sruvey(SF-36)was 0.513 (P<0.001).The test-retest reliability of the overall scale for one week was 0.812(P<0.001).The split-half reliability was 0.890(P<0.001).The internal consistency of the overall scale was 0.928.The differences in the scores of the scale for the participants with different social support were statistically significant.ConclusionRS-14 is good in validity and reliability and could be used in the evaluation of resilience among Chinese adults.
2013, 29(10): 1527-1528. doi: 10.11847/zgggws2013-29-10-39
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2013, 29(10): 1529-1532. doi: 10.11847/zgggws2013-29-10-40
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Prevalence and risk factors of hypertension in residents of Haidao town
JIANG Shi-zhen, ZHU Peng-li, YU Peng.et al
2013, 29(10): 1532-1534. doi: 10.11847/zgggws2013-29-10-41
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Objective To study the prevalence and risk factors of hypertension in residents of Haidao town,Xiapu county,Fujian province,and to provide evidences for performing specific prevention and control measures for hypertension in insular areas.Methods The information about hypertension and its risk factors were collected among 1 408 residents over age of 30 years from 4 villages by a questionnaire survey and physical examination.Associations between the risk factors and hypertension were analyzed with chi-square test and logistic regression.Results The prevalence rate of hypertension in the residents was 38.5%.The logistic regression analyses indicated that age,heavy alcohol drinking,work intensity,and body mass index were influencing factors of hypertension with the odds ratios of 1.12,1.88,0.49,and 1.21,respectively.ConclusionPrevalence of hypertension in the residents was high.Reducing alcohol consumption,lowering weight,and increasing physical activity contribute to the prevention and control of hypertension.
2013, 29(10): 1535-1536. doi: 10.11847/zgggws2013-29-10-42
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2013, 29(10): 1537-1538. doi: 10.11847/zgggws2013-29-10-43
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2013, 29(10): 1539-1541. doi: 10.11847/zgggws2013-29-10-44
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2013, 29(10): 1541-1542. doi: 10.11847/zgggws2013-29-10-45
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2013, 29(10): 1543-1545. doi: 10.11847/zgggws2013-29-10-46
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2013, 29(10): 1545-1546. doi: 10.11847/zgggws2013-29-10-47
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Change trend of bibliometric indicators of Chinese Journal of Public Health,2005 to 2011
PAN Wen, XIU Qiao, ZHENG Xin.et al
2013, 29(10): 1547-1549. doi: 10.11847/zgggws2013-29-10-48
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Objective To analyse bibliometric indicators of Chinese Journal of Public Health from 2005 to 2011.Methods Citation index and source periodicals index of periodicals were collected from Chinese Journal Citation Reports from 2006 to 2012,and the stability index,the average increases of the indexes were calculated.Results During the period,the overall cited frequency for Chinese Journal of Public Health was 3 524 with a mean of impact factor of 0.565;the mean of subject impact index was 0.89;the mean of subjects diffusion index was 8.95,and the mean ratio of the papers supported by various study funds was 0.62.There were obvious variations in the overall cited frequency,impact factor,immediacy index,and number of citied journals,whereas the subject diffusion index and other indexes remained stable,but cited rate,index of diffusion of subject,literature source,and the number of institutions of the authors declined during the period.ConclusionCitation index and source periodicals index of Chinese Journal of Public Health showed an increase trend from 2005 to 2011,with a higher rank in comprehensive evaluation for scientific journals on preventive medicine.
2013, 29(10): 1549-1552. doi: 10.11847/zgggws2013-29-10-49
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2013, 29(10): 1553-1555. doi: 10.11847/zgggws2013-29-10-50
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2013, 29(10): 1556-1558. doi: 10.11847/zgggws2013-29-10-51
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2013, 29(10): 1559-1560. doi: 10.11847/zgggws2013-29-10-52
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