Advance Search

2015 Vol. 31, No. 7

Display Method:
Mortality and characteristics of malignant tumor death among male residents in 6 cites of Liaoning province,2013
XING Li-ying, LIU Li, LI Yan-xia.et al
2015, 31(7): 951-953. doi: 10.11847/zgggws2015-31-07-27
Abstract(816) HTML (194) PDF 883KB(97)
Abstract:
Objective To examine the level and characteristics of malignant tumor deaths among residents in 6 cities of Liaoning province in 2013,and to provide a basis for malignant tumor control.Methods Data on mortality of the residents were extracted from Death Registry System and population data were collected from Liaoning Provincial Statistics Bureau; the causes of all deaths were coded by using International Classification of Diseases,Tenth Edition(ICD-10).Results The crude mortality rate of malignant tumor among male residents in 2013 was 208.94/100 000 and the standardized mortality rate was 132.58/100 000; deaths from malignant tumor accounted for 28.2% of all deaths.The malignant tumors with top 10 mortalities were lung,liver,stomach,colorectal anal cancer,esophageal cancer,pancreatic cancer,lymphoma,leukemia,lymphoma,and brain and central nervous system cancer,with an overall mortality of 180.21/100 000 and an overall standardized mortality rate of 114.29/100 000 and accounting for 86.3% of all malignant tumor deaths.The malignant tumor mortality rate increased with the increment of age among the male residents,with a lower level among the males aged 40 years or younger and the highest mortality among the males aged 85 years or older.Conclusion The characteristics of malignant tumors death is different among the residents with different age and living in different areas in 6 cities of Liaoning province in 2013.Comprehensive measures need to be promoted to decrease the mortality of malignant tumor among the residents.
Effects of HRS on apoptosis-related protein Bcl-xL,Bad,Bcl-2,and Bax and on myocardial ischemia-reperfusion injury in rats
LI Bo, YANG Meng, LIU Jing-wei.et al
2015, 31(7): 889-892. doi: 10.11847/zgggws2015-31-07-09
Abstract(1039) HTML (248) PDF 923KB(54)
Abstract:
Objective To study effects of hydrogen saturated saline(HRS) on expressions of apoptosis-related protein Bcl-xL,Bad,Bcl-2,and Bax and on myocardial ischemia-reperfusion injury in rats.Methods Thirty-six healthy male Sprague-Dawley(SD) rats were randomly divided into 3 groups(12 in each group):sham operation group(A),ischemia-reperfusion injury group(B),and HRS-treated group(C).Myocardial ischemia-reperfusion injury model was constructed using conventional method and a two hours reperfusion was performed after the establishment of the model among the rats of the 3 groups,and then the expressions of Bcl-xL,Bad,Bcl-2,and Bax were determeine.Results Compared to those of group C,left ventricular diastolic pressure(LVDP) and maximal first derivative of left ventricular diastolic pressure(LV Dp / dtmax) was significantly higher in group B.The observations with hematoxylin-eosin(HE) staining revealed cardiac cells arranged neatly in group A,obvious myocardial infarction in group B,and significantly reduced scope of infarction of cardiac cells in group C.The expressions of Bcl-xL and Bcl-2m RNA and protein were the highest in group A and the expressions in group C were significantly higher than those in group B(all P<0.05).Bad and Bax mRNA and protein expressions were the lowest in group A and the highest in group B,and the expressions in group C were significantly lower than those in group B(all P<0.05).Conclusion HRS can regulate apoptosis-related protein expressions of Bcl-xL,Bad,Bcl-2,and Bax and effectively reduce myocardial ischemia and reperfusion injury.
Treatment outcome of different doses of rosuvastatin on PCI patients with acute coronary syndrome
WANG Qiang, ZHANG Hong-yan, HU Yu-xia.et al
2015, 31(7): 959-962. doi: 10.11847/zgggws2015-31-07-30
Abstract(1022) HTML (147) PDF 906KB(116)
Abstract:
Objective To explore therapeutic effect of different doses of rosuvastatin in the treatment of percutaneous transluminal coronary intervention(PCI)patients with acute coronary syndrome(ACS)and to provide evidences for ACS treatment.Methods Totally 150 ACS patients receiving PCI in a hospital from December 2013 through December 2014 were randomly divided into A,B,and C group(50 in each group)and administrated with rosuvastatin at the doses of 5,10,and 20 mg/d,respectively,for 3 months;related indicators were compared among the three groups before and after the treatment and major cardiovascular events(MACE)and adverse reactions were observed.Results After the treatment,serum levels of hypersensitive C-reactive protein(hs-CRP)were 3.85±0.39,3.68±0.41,and 2.52±0.32 mg/L and those of brain natriuretic peptide(BNP)were 341.54±72.17,325.15±80.52,and 264.26±56.49 pg/ml for the patients in group A,B,and C,with significant differences compared to those of before the treatment(all P<0.05);the contents of hs-CRP and BNP of the patients of group C were significantly lower than those of group A and B(both P<0.05).Serum levels of total cholesterol(TC),triglyceride(TG),and low-density lipoprotein(LDL-C)in the patients of group C were 3.30±0.48,1.23±0.34,and 1.83±0.20 mmol/L,all lower than those before the treatment(all P<0.05)and lower than those of group A and B(all P<0.05).No significant statistical differences in serum alanine aminotransferase(ALT)and creatine kinase(CK)were observed among the three groups before and after treatment(all P>0.05).The incidence of MACE in group C was lower than that in A and B group,but MACE incidence of the three groups showed no significant statistical difference after the treatment(χ2=4.113,P=0.128);the incidence of adverse reactions in group C also was not significantly different from that of in group A and B(Fisher's exact P=0.504).Conclusion High-dose rosuvastatin can significantly decrease inflammation and serum BNP level in ACS patients,with effective and safety regulation of serum lipids,and could be applied in the treatment of ACS patients with PCI.
Effect of antiviral treatment on quality of life and its influencing factors among chronic hepatitis C patients
ZHU Ren-ying, KONG Xiang-hong, LANG Yu-ling.et al
2015, 31(7): 945-947. doi: 10.11847/zgggws2015-31-07-25
Abstract(1187) HTML (259) PDF 895KB(61)
Abstract:
Objective To explore the quality of life(QOL) and its influencing factors in chronic hepatitis C patients after antiviral treatment.Methods Totally 150 chronic hepatitis C inpatients aged 20-58 years were recruited and treated with antivirals from January to December 2013 in a general hospital in Mudanjiang city.The 36-item Short Form Health Survey(SF-36)was employed to evaluate the QOL of the participants one week before the treatment and one month,6 months,and one year after the treatment.Results The scores of QOL of the participants were 64.28±7.16,75.62±11.26,and 85.16±14.31 at 1,6,and 12 month after the treatment and significantly higher than that(49.61±4.13)before the treatment(all P<0.05).Compared to the females,the male participants had a significantly higher QOL score(81.76± 8.89 vs.51.56± 5.84)one year after the treatment(P<0.05).The QOL scores for physical functioning,role physical,bodily pain,general health,and social functioning were inversely correlated with age among the participants at one year after the treatment.The participants with the education of college or above had a significantly higher QOL score than those with the education below college level(82.54±8.08 vs.54.16±4.35,P<0.05) and the participants from the households with better condition had a significantly higher QOL score than those from households with general condition(79.46±8.64 vs.59.34±5.29,P<0.05).Conclusion Antiviral treatment can improve QOL of chronic hepatitis C patients but more attentions should be paid to QOL of women and the elderly with chronic hepatitis C.
Effect of long-term desalinated seawater consumption as drinking water on blood lipids in rats
DUAN Lian, WEI Lan, ZHANG Shao-pin.et al
2015, 31(7): 897-900. doi: 10.11847/zgggws2015-31-07-11
Abstract(794) HTML (126)
Abstract:
Objective To observe the effect of long-term consumption of desalinated seawater as drinking water on blood lipids in rats.Methods A total of 120 Wistar rats were divided into an experimental group drinking desalinated seawater and a control group drinking municipal tap water for one year.The blood samples of the rats were collected at 3,6,and 12 month.The indicators of blood lipid such as triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C)and low-density lipoprotein cholesterol(LDL-C)were analyzed with automatic biochemical analyzer.Results In the observation period,food-taking,drinking,and general state of the rats in the experimental group were normal and the change of body weight showed no obvious difference between the rats of the experimental and the control group.At 6 month,serum TC(1.52±0.18 mmol/L),HDL-C(0.90±0.14 mmol/L),and LDL-C(0.17±0.03 mmol/L) of the female rats in the experimental group were significantly higher than those of the rats in the control group(all P<0.05);serum TC(1.82±0.24 mmol/L),HDL-C(0.901±0.14 mmol/L)of the male rats in the experimental group were significantly lower than those of the rats in the control group(both P<0.05).At 12 month,serum TG(2.01±0.63 mmol/L),TC(1.20±0.30 mmol/L),HDL-C(0.71±0.11 mmol/L),and LDL-C(0.15±0.03 mmol/L)of the female rats in the experimental group were significantly lower than those of the female rats in the the control group(all P<0.05).Conclusion Long-term consumption of desalinated seawater as drinking water has no significant effect on the growth and development of rats but may influence blood lipid level of the female rats.
Change trend in diabetes prevalence and related factors among 60-79 years old residents in Chaoyang district of Beijing,2008-2014
WANG Yin-hui, HAN Xiao-yan, LI Zhe.et al
2015, 31(7): 907-911. doi: 10.11847/zgggws2015-31-07-14
Abstract(967) HTML (237) PDF 907KB(125)
Abstract:
Objective To analyze changes in diabetes prevalence and its risk factors among residents aged 60-79 years in Chaoyang district of Beijing from 2008 through 2014.Methods The elderly residents were selected with multistage stratified sampling in 2008 (n=750),2011(n=1 510),and 2014(n=532) and investigated with a same questionnaire,physical examination,and laboratory test.Results The annual diabetes prevalence were 18.9%,19.1%,and 21.1%,and the age-adjusted prevalence were 10.9%,10.2%,and 10.8% for the year of 2008,2011,and 2014 and the prevalence increased with the age(χtrend2=9.351,P=0.025).Significant yearly differences were observed in the prevalence of diabetes among the residents with different living area(urban or rural) and statuses of central obesity,smoking,alcohol drinking,and blood pressure(all P <0.01).Multivariate logistic regression analysis showed that hypertension and central obesity were risk factors of diabetes in 2008;male gender,hypertension and dyslipidemia were risk factors in 2011;alcohol drinking and effective exercise were protective factor;while elder age and dyslipidemia were risk factors in 2014.Conclusion Diabetes prevalence increased among 60-79 years old residents in Chaoyang district of Beijing between 2008 and 2014 and gender,age,hypertension,central obesity,dyslipidemia,alcohol consumption,and effective exercise were the main influencing factors of the disease in the elderly.
Impacts of capability for work,mental health,and coping style of nurses on hospital workplace violence
WANG Chao, SUN Chun-hua
2015, 31(7): 941-945. doi: 10.11847/zgggws2015-31-07-24
Abstract(1240) HTML (338) PDF 909KB(102)
Abstract:
Objective To investigate the impact of nurses' capability for work,mental health,and coping style on occurrence of hospital workplace violence and to provide references for the prevention of hospital workplace violence.Methods With random sampling,240 nurses were selected from a hospital and surveyed were with a self-designed general questionnaire,Workplace Violence Event Scale(WVS),Work Ability Index Inventory(WAI),Symptom Checklist-90(SCL-90),and Trait Coping Style Questionnaire(TCSQ).Logistic regression was adopted to analyze the associations of capability for work and coping style of the nurses with hospital workplace violence.Results Of the nurses,88(36.67%)were exposed to workplace violence events in the hospital during previous one year.For all the nurses,the average score of capability for work was 32.25±3.15;the average scores for positive and negative coping style were 38.26±4.25 and 31.85±5.42;the average total SCL-90 score was 25.96±5.36 and the domain scores were 2.09±0.82 for anxiety,2.18±0.88 for depression,2.20±0.91 for hostility,2.14±0.86 for paranoia,2.08±0.84 for paranoid,2.02±0.92 for somatization,2.11±0.71 for interpersonal sensitivity,2.18±0.850 for obsessive-compulsive symptoms,2.58±0.79 for psychosis,and 2.52±0.83 for other symptoms,respectively.Multivariate logistic regression analysis showed that working on night duty during the previous one month,with higher SCL-90 domain scores for the interpersonal sensitivity and hostility were risk factors for involvement of hospital workplace violence,while with higher capability for work and positive coping style were protective factors.Conclusion The involvement of hospital workplace violence is prevalent among nurses and capability for work,mental health,and coping style of the nurses have impacts on the occurrence of hospital workplace violence.
Urinary biomarker levels of polycyclic aromatic hydrocarbons in general population
WANG De-jie, SUN Zhi-tao, YANG Chao.et al
2015, 31(7): 977-980. doi: 10.11847/zgggws2015-31-07-35
Abstract(1222) HTML (216) PDF 907KB(226)
Abstract:
Polycyclic aromatic hydrocarbons(PAHs),as members of a family of environmental pollutants widely existing in the environment,showed potential carcinogenicity.Single biomarker cannot completely represent the internal body burden.Many studies for the biomonitoring of occupational PAHs exposure have been reported.However,less studies have been published relatively for the general population exposed to PAHs.This article reviewed the urinary biomarkers,with focus on their levels of PAHs exposure in general population from studies published after the year of 2 000.
Measles-related knowledge,attitude and behavior among college students in Weifang city
TAO En-xue
2015, 31(7): 938-940. doi: 10.11847/zgggws2015-31-07-23
Abstract(963) HTML (205) PDF 894KB(99)
Abstract:
Objective To examine measles-related knowledge,attitude,and behavior among college students in Weifang city and to provide evidences for carrying out health education and developing prevention and control measures.Methods With stratified cluster random sampling,1 573 college students from two colleges in Weifang city were surveyed with a self-designed questionnaire.Results The average score of measles-related knowledge was 6.3(out of 12 points)and the median score was 6.39;the pass rate of measles-related knowledge was 31.02% among the students.There were no statistically significant differences in measles-related knowledge level among the students with different ethnic,from different regions,and whether taking part in education program previously,but there were significant differences in the level among the students of different majors,gender,and registered permanent residence place(all P<0.01).The main ways to get measles-related knowledge were from television(47.55%),newspapers and magazines(45.65%),and networks(43.42%),respectively.Overall 95.10%of the students were willing to be vaccinated against measles.Conclusion The awareness of measles-related knowledge among college students in Weifang city was generally low,suggesting education on measles-related knowledge should be carried out in colleges.
Prevalence and influencing factors of overweight and obesity among adult residents in Shijiazhuang city
ZHANG Yan-ting, GAO Cong, MA Li-xin
2015, 31(7): 948-950. doi: 10.11847/zgggws2015-31-07-26
Abstract(1016) HTML (206) PDF 890KB(137)
Abstract:
Objective To investigate the prevalence and risk factors of of overweight and obesity among the adults living in Shijiazhuang city.Methods With multi-stage randomized cluster sampling,9 605 adults aged ≥18 years and living in the city at least 6 months were selected from 9 urban and suburb districts of Shijiazhuang and a face-to-face questionnaire survey and physical examination were carried out among the participants.Results The overall prevalence rate of overweight and obesity was 53.5% and the rate were 34.1% for overweight and 19.4% for obesity.Significant differences were found in the prevalence rate of overweight and obesity among the residents of different gender,age,education,marital status,alcohol drinking,sleeping,and the time of on web and watching television(all P<0.05).The results of logistic regression showed that the risk factors for overweight and obesity in the adults included aged 30 years or older,with marital status of married or cohabitation,divorced or widowed or separated,and alcohol drinking;with the education of less than 9 years and more than 6 years was a protective factor.Conclusion The prevalence of overweight and obesity needs to be concerned and its main risk factors are age,education,marital status,and alcohol drinking among the adults in Shijiazhuang city.
Prevalence and influencing factors of chronic diseases in residents aged 15 years and above in urban and rural areas of Yunnan province,2010-2012
ZHAO Jiang, WAN Rong, LIU Zhi-tao.et al
2015, 31(7): 878-882. doi: 10.11847/zgggws2015-31-07-06
Abstract(1142) HTML (268) PDF 907KB(91)
Abstract:
Objective To analyze the prevalence of chronic diseases and its influencing factors in the residents aged 15 years and above in urban and rural areas of Yunnan province in 2010-2012.Methods A total of 5 434 urban and rural residents aged 15 years and above were selected from Panlong,Gejiu,Shuifu,Menglian,Ninglang,and Luxi country of Yunnan with multi-stage random cluster sampling and investigated with a face-to-face questionnaire survey.Multiple factors analysis was performed with non-conditional logistic regression.Results Among the participants,the prevalence rate of overweight or obesity,hypertension,diabetes,dyslipidemia,and stroke were 16.2%,9.3%,13.3%,23.2%,and 0.8%,respectively,during 2010-2012.After adjusting for potential confounding factors,the results of logistic regression revealed that the risk factors of chronic diseases were Hani nationalities(odds ratio[OR]=2.885,P=0.000),with history of physical examination(OR=1.268,P=0.000),and drinking wine(OR= 1.315,P=0.038)and the protective factors were married(OR=0.502,P=0.000),Miao nationality(OR=0.609,P=0.035),living in poverty-stricken areas in Ninglang(OR=0.365,P=0.000) and Menglian(OR=0.551,P=0.007)county,non-smoker(OR=0.829,P=0.009),and strong alcohol-drinking(OR=0.734,P=0.002).Conclusion The prevalence of chronic diseases in residents aged 15 years and above in urban and rural areas of Yunnan province should be concerned and the prevalence was influenced by ethnicity,marital status,living area,history of physical examination,smoking,and alcohol use.
Application of autoregressive integrated moving average model in incidence rate prediction of hemorrhagic fever with renal syndrome in Shen-zhen city
MEI Shu-jiang, ZHOU Zhi-feng, MA Han-wu.et al
2015, 31(7): 936-938. doi: 10.11847/zgggws2015-31-07-22
Abstract(1116) HTML (270) PDF 894KB(134)
Abstract:
Objective To establish an autoregressive integrated moving average(ARIMA) model for epidemic trend prediction of hemorrhagic fever with renal syndrome(HFRS)in Shenzhen city.Methods ARIMA model was established based on the monthly incidence rate of HFRS in Shenzhen city from 2005 through 2013.The constructed optimal model was applied to predict the incidence rate of HFRS in Shenzhen city in 2014 and to evaluate the validity of the model through comparing the difference of predicted incidence rate and actual one.The incidence rate of HFRS in 2015 was predicted by the ARIMA model based on the incidence rate from 2005 through 2014.Results The model of ARIMA(1,0,1)(1,0,1)12 had a good fitness to the incidence rate and all parameters(AR=0.993,MA=0.926,SAR=0.967,SMA=0.857)of the model were statistically significant(P<0.01)and Schwarz Bayesian criterion(BIC)=-3.300.The residual error was white noise and the Ljung-Box test statistics for the model was 20.794,with a P value of 0.107.The predicted incidence rate in 2014 was consistent with the actual one,with the relative error of 20.74%.The predicted incidence rate of HFRS in 2015 based on the incidence rate from 2005 through 2014 is 4.28 per billion.Conclusion ARIMA model can be used to simulate changes in HFRS incidence rate and to forecast the incidence rate in future in Shenzhen city.
Polymorphism of HOXA10 gene among female infertility patients
FU Mian-ai, HUANG Lin, XIAN Mei-lan.et al
2015, 31(7): 958-959. doi: 10.11847/zgggws2015-31-07-29
Abstract(1001) HTML (228) PDF 877KB(119)
Abstract:
Objective To explore the polymorphism of HOXA10 gene among female infertility patients in Hainan province.Methods We selected 220 female infertility patients seeking medication in a hospital during 2013 July to July 2014 and collected their venous blood samples for genomic DNA extraction and analysis of single nucleotide polymorphism (SNP) of rs3779456 of HOXA10 gene.Results The frequencies of CC,CT,and TT of rs3779456 of HOXA10 were 36.36%,20.91%,and 42.73% among patients and the allele frequency of C and T were 46.82% and 52.18%.Conclusion There are three genotypes for 2 alleles of rs3779456 of HOXA10 gene among female infertility patients in Hainan province.
Influential factors of hospitalization among rural residents in Haiyuan county of Ningxia
HUANG Ya-xin, QIAO Hui, REN Hai-li
2015, 31(7): 883-885. doi: 10.11847/zgggws2015-31-07-07
Abstract(950) HTML (192) PDF 893KB(66)
Abstract:
Objective To study the status and influence factors of hospitalization among rural residents in Haiyuan county of Ningxia Hui Autonomous Region(Ningxia).Methods With multi-stage stratified cluster sampling,a total of 11 848 rural residents in Haiyuan county of Ningxia were investigated with a household questionnaire survey.Results Of the residents surveyed,1 255 required hospital admission during the period and the presumed hospitalization rate was 6.7%.The proportion of non-hospitalization among the ill residents requiring hospitalization was 17.9%.Univariate analysis showed that the presumed hospitalization rate for the Han residents was 5.8% and that for the Hui was 6.7%,with a statistically significant difference(χ2=8.214,P=0.016).The presumed hospitalization rate in the residents increased with age and was significantly different among the residents of different age groups(χ2=596.479,P<0.01); the presumed hospitalization rate was also significantly different among the residents with various marital status(χ2=153.073,P<0.01) and was low in those unmarried(2.8%); the presumed hospitalization rate decreased with the increase of educational level(χ2=194.628,P<0.01).Multivariate analyses showed that being Hui nationality(odds ratio[OR]=1.158),at older age(OR=3.246),suffering from chronic disease(OR=3.246),and being ill within the two weeks before the survey(OR=3.496)were risk factors for the requirement of hospital admission; with a higher education level(OR=0.752)was a protective factors for the requirement of hospital admission.Conclusion The presumed hospitalization rate among rural Hui residents,children,elderly persons,and the people with poor health is relatively high in Haiyuan county of Ningxia.
Progress in researches on biological monitoring of chronic low dose pesticide exposure
DENG Yuan-ying, HE Wei, TIAN Jing.et al
2015, 31(7): 900-903. doi: 10.11847/zgggws2015-31-07-12
Abstract(1145) HTML (267) PDF 909KB(163)
Abstract:
The biological monitoring of chronic low dose pesticide exposure has important implications for evaluating the effects of pesticide exposure on human health.The methods of biological monitoring were reviewed in the article.The biomonitoring samples include urine,blood,saliva,sweat and hair.The biomarkers include chemicals and metabolites of pesticides.Meanwhile,some indirect indexes such as enzyme,DNA,neurotransmitter,protein were also used as biomarkers of pesticide exposure.Appropriate method of biological monitoring can provide an efficient and cost-effective way to identify and quantify pesticide exposure.
Advance in researches on relationship between gut microbiota and obesity
WANG Ning, BAO Yan
2015, 31(7): 973-976. doi: 10.11847/zgggws2015-31-07-34
Abstract(1217) HTML (775) PDF 897KB(193)
Abstract:
Intestinal flora plays an important role in the development of obesity.Intestinal microbial species and proportions are closely related to obesity,and intestinal flora interacts with diet to regulate energy metabolism through the interaction of the host.The changing of intestinal flora can also lead to excessive toxin;inflammation,and fat metabolic syndrome.This article gives an account of achievements in the researches on gut microbes associated with obesity in recent years.
Depressive symptoms and associated factors among seamen undertaking international voyage
MEI Yang, ZHANG Jie, LI Feng.et al
2015, 31(7): 954-957. doi: 10.11847/zgggws2015-31-07-28
Abstract(1294) HTML (260) PDF 902KB(90)
Abstract:
Objective To examine the status of depressive symptoms and its impact factors among the seamen engaged in international voyage.Methods By using cluster sampling,we recruited 719 Chinese seamen who came from international voyage ships anchored in Nantong and Rugao port and had entry-exit physical examination and vaccination in Nantong International Travel Health Care Center during April to December of 2012. A face-to-face interview was conducted among the seamen with a self-designed questionnaire and Self-Rating Depression Scale(SDS). Chi-square test and multivariate logistic regression were used in data analyses.Results Of the seamen,354(49.24%)had no depressive symptoms,whereas 167(23.23%),186(25.87%),and 12(1.67%)had mild,moderate,and severe depressive symptoms,respectively. Multivariate logistic regressions showed that with the education of college and above(odds ratio[OR]=0.482)or undergraduate(OR=0.396),having sleeping time of 8 to 9 hours(OR=0.50)or more than 10 hours(OR=0.193)were the protective factors of depressive symptoms;having leisure activities of 8 to 14 hours(OR=2.846)or less than 7 hours(OR=1.393)per week,with an ordinary(OR=2.642)or bad(OR=3.477)self-reported health status were the risk factors.Conclusion Depression symptom is a serious problem and is mainly affected by educational level,sleeping time,the time of weekly leisure activity,and self-reported health among the seamen undertaking international voyage.
Prevalence of knee osteoarthritis among Uighur,Kazak,Han residents living in pastoral area of north Xinjiang
WANG Xin-jun, LIU Jun-chang, Muhetaer·Ayoufu.et al
2015, 31(7): 853-855. doi: 10.11847/zgggws2015-31-07-01
Abstract(1207) HTML (308) PDF 896KB(65)
Abstract:
Objective To examine the prevalence of knee osteoarthritis(KOA)among inhabitants of Uighur,Kazak,and Han nationality in pastoral areas of north of Xinjiang Uygur Autonomous Region(Xinjiang)and to provide evidences to local health administrative departments for making relevant health policy.Methods Cluster random sampling method was used to select 3 402 Uighur,Kazak,Han residents in Yili,Tacheng,and Aletai in pastoral areas of north Xinjiang for a questionnaire survey and examination of knee joint.Results In the participants,the prevalence of KOA was 27.0%;the prevalence of KOA in the males was 18.6% and significantly lower than that in the females(34.8%)(χ2=113.36,P<0.01);the prevalence rates of KOA were 21.5%,31.6%,and 31.7% for the residents aged 38-49,50-59,and more than 60 years,with a statistically significant difference among different age groups(χ2=46.59,P<0.01);the KOA prevalence rates were 24.2%,37.7%,and 19.3% for the residents living in Yili,Tacheng and Aletai area,with statistically significant regional difference(χ2=93.01,P<0.01);the KOA prevalence rates were 29.6%,35.1%,and 18.1% for Uygur,Kazak and Han residents,with a statistically significant difference among different ethnic groups(χ2=89.83,P<0.01).Conclusion The prevalence rate of KOA is high and there are gender,age,ethnic,and regional differences in the prevalence rate among Uygur,Kazak,and Han residents in pastoral areas of north Xinjiang.
Psychoactive drug use for non-medical purpose among middle school students in Guangdong province
WANG Wan-xin, DENG Jian-xiong, GUO Lan.et al
2015, 31(7): 856-858. doi: 10.11847/zgggws2015-31-07-02
Abstract(973) HTML (236) PDF 896KB(63)
Abstract:
Objective To investigate the prevalence of psychoactive drug abuse among middle school students in Guangdong province and to provide evidences for the management of psychoactive drugs.Methods A total of 21 449 students from 12 schools were recruited with three-stage cluster sampling.Results Among all the respondents,10.37% reported psychoactive drugs use without medical purposes,and the abuse rate showed a significant difference among schools(P<0.001).Among the students,4.5% reported the usage of compound liquorice tablet at any time;1.56% and 0.97% reported the usage of Akafen powder during previous 12 months and 30 days.Among the students reporting history of psychoactive drug use,65.03% used the drugs firstly at the time of first year into or before entering the high school;38.29%got the drugs they used from home and 38.29% used the drugs for releasing the pressure.Conclusion Psychoactive drug use for non-medical purpose is prevalent and compound liquorice tablet and Akafen powder are most frequently used drugs among middle school students in Guangdong province.
Prevalence and risk factors of chronic hepatobiliary diseases among rural native Tibetan dwellers in Lhasa
Gonggalanzi, Baimakangzhuo, CUI Chao-ying.et al
2015, 31(7): 859-863. doi: 10.11847/zgggws2015-31-07-03
Abstract(1180) HTML (336) PDF 910KB(89)
Abstract:
Objective To investigate the prevalence and risk factors of chronic hepatobiliary diseases among rural native Tibetan dwellers in Lhasa,Tibet and to provide evidences for making intervention strategies for the diseases.Methods A self-administrated questionnaire survey,physical examination,and type-B ultrasound and liver function test were conducted among 1 737 adult native Tibetans(≥18 years old) selected with stratified random sampling from rural areas of Mozhugongka and Linzhou county of Lhasa municipality.Results The overall prevalence of chronic hepatobiliary diseases among the dwellers was 22.3%,with the prevalences of 11.3% for cholecystitis,6.2% for cholelithiasis,4.5% for hepatic adipose infiltration,1.9% for hepatic echinococcosis,1.6% for hepatic hemangioma,and 0.8% for cirrhosis,respectively.The main risk factors of the chronic hepatobiliary diseases were female gender,aged ≥45 years,with average monthly income of >2 000 yuan RMB,overweight,obesity,central obesity,and increased alanine transferase(ALT) based on the results of multivariate unconditional logistic regression.Conclusion Cholecystitis is one of major chronic hepatobiliary diseases among rural native Tibetan dwellers in Lhasa and females,the elderly,the dwellers with higher average monthly income,body mass index,increased ALT,and central obesity are the key populations for the prevention and teatment of chronic hepatobiliary diseases in the areas.
Mediation effect of coping style on relationship between perceived stress and job burnout among science and technology professionals
GUO Bing-xin, WANG Yong-guang, WANG Yi-qiang.et al
2015, 31(7): 863-869. doi: 10.11847/zgggws2015-31-07-04
Abstract(1055) HTML (273) PDF 1140KB(125)
Abstract:
Objective To study the status quo of job satisfaction and to explore the mediation effect of coping style on the relationship between perceived stress and job burnout among science and technology professionals(STPs).Methods Totally 2 730 STPs in Zhejiang province were assessed with Maslach Burout Inventory-General Survey(MBI-GS),Perceived Stress Questionnaire,and Trait Coping Style Questionnaire(TCSQ)to evaluate their job burnout,perceived stress level,and coping styles.Results Among the STPs,the domain scores of MBI-GS were 1.90±0.94 for emotional exhaustion,1.38±0.94 for cynicism,and 2.42±1.17 for low sense of achievement;the score of perceived stress was 41.06±16.85;and the TCSQ scores were 33.97±6.75 and 24.63±6.31 for positive and negative response.The positive and negative response played a partial mediation effect on the relationsip between perceived stress and emotional exhaustion and on the relationship between perceived stress and cynicism,with the total effect ratios of 0.154 and 0.170;the positive and negative response also play a complete mediation effect on the relationship between perceived stress and low sence of achievement,with the the total effect ratios of 0.985 and 0.500.Conclusion Coping style plays a mediation effect on the relationship between perceived stress and job burnout among STPs in Zhejiang province.
Changes of time and space differences in health status and their influencing factors among the elderly in China
DU Ben-feng, GUO Yu
2015, 31(7): 870-877. doi: 10.11847/zgggws2015-31-07-05
Abstract(1181) HTML (298) PDF 1127KB(76)
Abstract:
Objective To examine spatial and temporal variations in health disparities among Chines elderly and their influencing factors and to provide references for improving the health of the elderly.Methods We extracted health-related data of 45 244 elderly involved in 3 waves of cross-sectional survey in 2002,2005 and 2008 for the ‘Follow-up Study on Elderly Longevity in China’ conducted by Peking University and China Aging Research Center in 22 provinces at north,northeast,east coast,and midwest region of China.We adopted ArcGIS10 in spatio-temporal change analysis on health of the elderly and multiple linear model in analysis on influence factors of the changes.Results Self-rated health was poor among the elderly in underdeveloped areas of China in 2002-2008.The self-rated health status of the elderly in middle east was better than those in the western region,with obvious internal differences.The analyses on time variable coefficient-related fixed effects revealed that the descent rate of self-rated health for the elderly aged 65-80 years was 0.09 higher than those over 80 years old and the rate of the elderly men was 0.03 higher than the older women in China.The descent rate of self-rated health for the Han elderly was 0.04 higher than that of the minority elderly.The elderly with non-agricultural occupation before the age of 60 years had a 0.03 increase in self-rated health ascent rate.Whether having adequate living expenses and whether having physical exercise have negative prediction function on the change trend of self-rated health,whereas,being capable of taking care of oneself and not sufferings from chronic disease have positive prediction function for self-rated health.The elderly having serious disease had a 0.07 increase in self-rated health ascent rate.Conclusion There is a great regional disparity in self-rated health among Chinese elderly and the disparity changes with time.The main influence factors for self-rated health among Chinese elderly include age,gender,nationality,occupation before the age of 60 years,living expense,physical exercise,capability of taking care of oneself,and suffering from chronic disease.
Reproductive toxicity of n-hexane gestational exposure in male offspring rats
LI Hong, PAN Xue-feng, LU Xiao-li.et al
2015, 31(7): 886-889. doi: 10.11847/zgggws2015-31-07-08
Abstract(874) HTML (249) PDF 1030KB(68)
Abstract:
Objective To study reproductive toxicity of n-hexane gestational exposure in F1 Wista male rats.Methods Twenty-four pregnant Wistar rats were exposed to n-hexane at the concentrations of 0,360,1 800,and 9 000 mg/m3 via respiration for 4 hours a day from 1 to 20 gestation day.The male offspring(F1) rats were weighted every 3 days from postnatal day(PND) 9 and sacrificed at PND 69.Testis and epididymis organ coefficient,sperm survival ratio,sperm motility,sperm abnormality rate,and sperm density of the male F1 rats were observed.The testis tissues of the F1 male were consecutively sectioned and stained with hemotoxylin and eosin(HE) for microscopic observation of histopathological changes.Serum testosterone and malonaldehyde(MDA) in testis of the offspring rats were also measured.Results Compared with the control,body weight,testis organ coefficient,sperm survival ratio and motility,and serum testosterone were significantly declined and obvious dysplasia in testis was observed in the male rats with 9 000 mg/m3 n-hexane gestational exposure.No significant differences in MDA content of testicular tissue were observed among the rats with different concentrations of n-hexane gestational exposure.Conclusion Gestational exposure to high concentration of n-hexane could lead to obvious dysplasia of reproductive organ in male F1 rats and the dysplasia is not related to lipid peroxidation pathway.
Effect of Sacha Inchi oil on blood lipid,ApoAI,and ApoB in quails with hyperlipidemia
WANG Lin-yuan, WANG Chun, ZHANG Jian-jun.et al
2015, 31(7): 893-896. doi: 10.11847/zgggws2015-31-07-10
Abstract(1361) HTML (383) PDF 1005KB(70)
Abstract:
Objective To study the effect of Sacha Inhi oil on blood lipid,apolipoprotein AI(ApoAI),and apolipoprotein B(ApoB)in quails with hyperlipidemia.Methods Hyperlipidemia model was established with high-fat diet feeding in 50 quails and a control group(10 quails)was set with normal diet.Four groups(10 in each group)of hyperlipidmic quails were then administrated with 1.0,0.5,0.25 g/kg Sacha Inhi oil,and perilla oil intragastrically for four weeks and a model group(10 hyperlipidmic quails without further treatment)was set.At the end of the treatments,serum triglyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),ApoAI,and ApoB were determined and pathologic histology changes in liver were observed with hematoxylin-eosin staining.Results Compared with those of the controls,serum TC(14.23±1.766 mmol/L),TG(2.980±0.384 mmol/L),and LDL-C(8.284±0.727 mmol/L)were significantly higher and serum HDL-C(2.423±0.221 mmol/L)was significantly lower for the quails of model group(all P<0.01).Compared with those of the model group,serum TC(9.50±0.887 and 9.78±1.059 mmol/L),TG (1.662±0.198 and 1.778±0.433 mmol/L),and LDL-C(4.616±0.648 and 5.782±0.863 mmol/L)were significantly lower and serum HDL-C(4.916±0.424 and 4.247±0.702 mmol/L)were significantly higher for the quails in 1.0 and 0.5g/kg Sacha Inchi oil groups(all P<0.05).The level of ApoAI (0.050±0.006 g/L) of the model group was significantly lower than that of the control group(P<0.01),but the level of ApoB (0.110±0.016 g/L)was significantly higher(P<0.01).The level of ApoAI(0.077±0.011 g/L)of the 1.0 g/kg Sacha Inchi oil groups was significantly higher than that of the model group(P<0.05),while the level of ApoB(0.069±0.010 g/L)was significantly lower(P<0.05).Pathological examination revealed serious liver fatty degeneration,with dense areas of fat cavitation in liver cells,for the quails of model and the attenuated liver fatty degeneration was observed in the quails with Sacha Inhi oil of different dosages.Conclusion Sacha Inhi oil can regulate blood lipid in hyperlipidaemic quails and the effect may be related to the improvement of cholesterol metabolism through upregulation of ApoAI and downregulation of ApoB.
Detection and significance of calcium metabolism and indicators of calcium nutritional status in obese rats
YANG Qing, CHEN Jin-yu, YANG Ye-tong.et al
2015, 31(7): 904-906. doi: 10.11847/zgggws2015-31-07-13
Abstract(914) HTML (454) PDF 884KB(50)
Abstract:
Objective To study changes in calcium level and related metabolism indicators in obese rats and to provide evidences for the prevention and control of calcium malnutrition induced by obesity.Methods Twenty-five male Wistar rats were randomly divided into a control group(n=10) and an obesity model group(n=15); the rats in the two groups were fed with ordinary feed and high-fat diet,respectively,for 8 weeks and they were sacrificed and their eye blood samples were collected for detections of serum calcium,alkaline phosphatase,parathyroid hormone,calcitonin,calcium-binding protein,and vitamin D receptor.Results Compared with the control group,serum calcium was decreased and alkakine phosphatase increased in obese group significantly(both P<0.05).Compared with the control group,serum parathyroid hormone was increased and calcitonin decreased in obese model group significantly(both P<0.05). Compared with the control group,serum calcium-binding protein was decreased and vitamin D receptor increased in obese model group significantly(both P<0.05).Conclusion Obesity can lead to calcium deficiency and changes in calcium metabolism indices.Obese people should pay attention to the increase of dietary calcium intake.
Nutritional status among elderly inpatients in Hubei province
GONG Xun, WANG Xuan-xuan, ZHOU Shang-cheng.et al
2015, 31(7): 912-914. doi: 10.11847/zgggws2015-31-07-15
Abstract(863) HTML (161) PDF 895KB(88)
Abstract:
Objective To assess nutritional status and its influencing factors among senile inpatients in Hubei province and to provide references for rational nutrition support in elderly patients.Methods We selected 4 946 elderly patients(aged 60-86 years) hospitalized in general hospitals in 5 prefectures in Hubei province from May through December 2014 using stratified random sampling and assessed nutritional status of the elderly inpatients with physical examination and laboratory test based on the criteria of nutrition risk screening(NRS),2012.Results The obesity rate were 34.16% and 15.44% for the inpatients from urban and rural areas,with a statistically significant difference(χ2=30.47,P<0.05).Among the elderly inpatients,53.62% were at a risk of malnutrition based on NRS assessment;44.54% had anemia;and the abnormal rates were 53.98% for serum total protein(TP),59.12% for blood albumin(ALB),43.17% for total lymphocyte count(TLC),and 39.39% for red blood cell count,respectively.There were significant differences in the rate of anemia and abnormal rates of TP,ALB,and RBC between the inpatients from urban and rural areas(χ2=21.72,32.85,38.23,and 21.07;all P<0.05).Conclusion With the increment of age,rural elderly inpatients have an increased risk of malnutrition than urban elderly inpatients in Hubei province,suggesting more attentions should be paid to nutrition status of rural elderly inpatients.
Staple food consumption and related selenium intake among residents in Kashin-Beck disease endemic areas of Lhasa municipality,China
CHEN Zhuo, LI Hai-rong, YANG Lin-sheng.et al
2015, 31(7): 915-918. doi: 10.11847/zgggws2015-31-07-16
Abstract(865) HTML (186) PDF 891KB(71)
Abstract:
Objective To assess staple food consumption patterns and daily selenium(Se) intake through staple food among residents in Kashin-Beck disease(KBD) endemic areas of Lhasa municipality and to provide evidences for KBD control and prevention in Tibet. Methods Staple food consumption frequency questionnaires were completed by 105 local residents in Lhasa KBD endemic areas and Se concentrations of 268 staple food samples were determined. The average daily Se intake through staple food among the residents was evaluated. Results Among the residents,the proportions of consuming tsamba(made of home-grown highland barley and beans) twice per day,purchased rice and flour once per day or more were 72.4%,48.6% and 66.7%,respectively. The residents in pastoral areas reported a higher proportion of consuming purchased rice frequently compared to those living in farming areas and the residents in farming-pastoral areas reported the lowest proportion; the residents aged ≤ 39 years reported a significantly higher frequency of consuming purchased rice and flour than those aged ≥ 60 years(P< 0.05). Se concentration in the rice and flour purchased in Lhasa were 36.17 μg/kg and 29.31 μg/kg,which were 3.2-4.8 times higher than that of home-grown highland barley(9.07 μg/kg),self-made tsampa(9.63 μg/kg),and home-grown wheat(7.46 μg/kg). The average daily Se intake through staple food was 8.30 μg and 76.1% of total daily Se intake was contributed to the consumption of purchased rice and flour in the residents. Conclusion The increased intake of exogenous rice and flour with high Se content has a significant effect on enhancing Se intake among local residents in Lhasa. However,the consumption amount of home-grown staple food with low Se content is still relative high,especially in farming-pastoral areas.
Influence factors of medication awareness among patients with chronic diseases in Shandong province
ZHU Li-li, YIN Wen-qiang, HU Jin-wei.et al
2015, 31(7): 919-922. doi: 10.11847/zgggws2015-31-07-17
Abstract(1060) HTML (181) PDF 897KB(64)
Abstract:
Objective To examine influence factors of medication awareness among patients with chronic diseases in Shandong province and to provide references for promoting the patients to grasp right concept and rational application of medication.Methods With multi-stage stratified random sampling,we selected 1 518 households in Ji'nan,Ji'ning,Rizhao,Linyi,and Dezhou city in Shandong province for a questionnaire survey and recruited 516 residents with noncommunicable chronic diseases diagnosed within previous 6 month for a face-to-face interview on chronic disease medication and its related factors.Results Among the 516 patients,84.69% had medication for their chronic diseases and 67.31% had poor medication awareness.Of the patients,23.38%,24.94%,and 59.23% responded positively to the viewpoint of ‘therapeutic effect of new drugs being better definitely than that of conventional drugs’,‘expensive drugs being more effective than cheap drugs’,and combination of several drugs being better than having only one drug for disease treatment.Multivariate logistic regression analysis showed that the patients doing agricultural work(odds ratio[OR]=2.969,95%confidence interval[95%CI];1.716-5.139)and believing in medication advertisement(OR=3.048,95%CI:1.123-8.269)were more likely to have poor awareness of medication for chronic disease.Conclusion The medication awareness is poor and occupation and whether believing in medication advertisement are main influencing factors of the awareness among the patients with chronic diseases in Shandong province.
Umbilical cord blood concentration of heavy metals and its relationship with low birth weight among the newborns in Shaoguan city,Guangdong province
ZHOU Jin-hua, CHAN Fan-fan, HONG Ling-yao.et al
2015, 31(7): 922-925. doi: 10.11847/zgggws2015-31-07-18
Abstract(1010) HTML (215) PDF 891KB(96)
Abstract:
Objective To detect concentrations of heavy metals in umbilical cord blood of newborns and to explore its relationship with low birth weight among newborns in Shaoguan city of Guangdong province.Methods We used convenient sampling to select 1 036 pregnant women who giving birth to their children in two hospitals of Shaoguan city.The participants were asked to take a questionnaire survey and umbilical cord blood samples of the newborns were collected by well-trained doctors.Inductively coupled plasma mass spectrometry(ICP-MS) was used to measure the concentrations of heavy metals in the umbilical cord blood samples.Results The excessive rate of arsenic(As)was 72.49%,which was the highest among the heavy metals detected,and the excessive rate of stibium(Sb),selenium(Se),manganese(Mn),and barium(Ba)were 48.07%,34.07%,27.12%,and 14.48%,respectively.While,there were 93.24%,46.81%,94.11%,and 64.19% of the umbilical cord blood samples had lower concentrations of calcium(Ca),ferrum(Fe),cuprum(Cu),and zinc(Zn)than the reference range,respectively.All the heavy metals were associated with low birth weight except for Mn.The newborns with low birth weight had higher concentrations of As,Cd,Sb,and Ba,but lower concentrations of some essential metals such as magnesium(Mg),Ca,and Fe compared to those of the newborns with normal birth weight.Conclusion The results indicated that pollution of some heavy metals was serious but a number of newborns had lower concentrations of some essential metals than the reference range in the area surveyed,and the incidence of low birth weight among the newborns was associated with the concentrations of these metals in umbilical cord blood.
Seasonal variation in association between air pollution and ischemic heart disease mortality in Wuhan,China
ZHANG Yun-quan, WU Kai, ZHU Ci-hua.et al
2015, 31(7): 926-929. doi: 10.11847/zgggws2015-31-07-19
Abstract(1255) HTML (275) PDF 912KB(73)
Abstract:
Objective To explore the association between short-term exposure to ambient air pollution and ischemic heart disease(IHD)mortality as well as seasonal variation of the association in Wuhan city,China.Methods Data on daily IHD mortality for the period of 2002 through 2010 was obtained from Jiang'an District Center for Disease Control and Prevention,Wuhan and the data on concentration of relevant air pollution and meteorological factors from local municipal environmental monitoring center and meteorology bureau of Wuhan,respectively.Quasi-Poisson regression of generalized additive model was applied to evaluate the association between air pollution and IHD mortality,using both all-season and season-specific models.Results Ambient pollution level and IHD deaths reached highest in winter among the four seasons.Annual average concentrations of particulate matter less than 10 μm in aerodynamic diameter(PM10),sulfur dioxide(SO2),and nitrogen dioxide(NO2)in winter were 143.8±70.9 μg/m3,71.0±42.4 μg/m3,and 66.5±25.6 μg/m3,respectively,and 1.64 IHD deaths per day occurred in winter.In all-season model,a 10 μg/m3 increase in previous day(lag 1)for PM10 was associated with 0.86%(95%confidence interval[95%CI]:0.22%-1.51%)excess risk in IHD mortality and no statistically significant association between gaseous pollutants(SO2,NO2)and IHD mortality was found.The season-specific model showed that ambient pollutants were consistently associated with increased IHD mortality only in winter(from 1st of November to 28th of February)and a 10 μg/m3 increase in previous day(lag1)ambient pollutants was associated with 1.40%(95%CI:0.58%-2.23%)excess risk in IHD mortality for PM10,1.65%(95%CI:0.28%-3.05%)excess risk for SO2,and 3.05%(95%CI:0.92%-5.23%)excess risk for NO2,respectively.Conclusion In Wuhan city,short-term exposure to air pollution was associated with increased IHD death and a seasonal pattern with an obvious peak in winter was consistently found in the acute effects of both PM10 and gaseous pollutants(SO2,NO2)on IHD mortality.
Awareness of essential medicine institution and attitude toward essential medication free of charge among residents in Liaoyuan city
MA Jie, ZHANG Xiao-ying, ZHANG Wen-rui.et al
2015, 31(7): 930-932. doi: 10.11847/zgggws2015-31-07-20
Abstract(795) HTML (206) PDF 894KB(57)
Abstract:
Objective To examine the awareness of essential medicine institution and the attitude toward essential medication free of charge among residents in Liaoyuan city,Jilin province and to provide references for the feasibility and implements of the policy of essential medication free of charge for elderly people at grass-roots medical institutions.Methods Totally 280 elderly residents(aged 60-80 years)and 300 middle-aged residents(30-69 years old)were selected in Liaoyuan city with stratified random sampling and surveyed with a questionnaire.Results The proportion of the people without awareness of,having heard of,knowing a little about,and knowing well about essential medicine institution were 53.9%,19.6%,21.0%,and 5.4% among the elderly and 46.7%,26.7%,19.3%,and 7.3% among the middle-aged,respectively,and there was no significant difference in the awareness of essential medicine institution between the elderly and the middle-aged residents(P>0.05).The percentage of people suffering from diseases(42.1%)in the elderly was significantly higher than that in the middle-aged(25.7%)(χ2=17.62,P=0.000).The proportion of the people doing periodic physical examination while knowing very well about health status of oneself,seeing a doctor when feeling uncomfortable,and never doing physical examination nor seeing a doctor were 30.0%,62.1%,and 1.4% among the elderly and 28.7%,54.0%,and 17.3% among the middle-aged,respectively,and there was a significant difference in the awareness of health status between the two groups(χ2=11.93,P=0.003).There were significant differences in behaviors related to the attitude toward essential medication free of charge,such as the management of remaining medicine stored at home,whether using self free allowances for essential medication to buy drugs for family members,and the management of remaining free allowances for essential medication,between the elderly and the middle-aged residents(all P<0.05),but there was no significant difference in the consideration of reducing financial burden with the utilization of essential medication free of charge(P>0.05).Conclusion Most elderly people are sufferers of diseases and more willing to seek medication;the policy of essential medication free of charge at grass-roots medical institutions is feasible,however relevant risk in the implementation of the policy should be taken into consideration.
Prevalence of anti-HAV and anti-HEV IgM among employees in Guangzhou Baiyun International Airport
SUN Wei, LU Min, PAN De-guan.et al
2015, 31(7): 933-935. doi: 10.11847/zgggws2015-31-07-21
Abstract(1039) HTML (242) PDF 884KB(81)
Abstract:
Objective To examine the prevalence of anti-hepatitis A virus immunoglobulin M(HAV-IgM)and anti-hepatitis E virus immunoglobulin M(HEV-IgM)among employees in Guangzhou Baiyun International Airport for the assessment of HAV and HEV infection among the employees.Methods Serum samples of 35 995 physical examinees from the airport were collected for the determination of HAV-IgM and HEV-IgM with enzyme-linked immunoassay(ELISA)in March 2010 through December 2013;chi-square test and linear regression analysis were used in data analyses.Results The positive rate of HAV-IgM was 0.328% and that of the HEV-IgM was 0.253%.There were significant seasonal differences in the positive rate of HAV-IgM(χ2=21.86,P<0.001),with a higher positive rate in the summer and autumn and a lower rate in the spring.No seasonal difference in HEV-IgM positive rate was observed(χ2=3.67,P=0.299).Linear regression analyses showed that the HAV-IgM positive rate increased with the increment of age(t=4.360,P=0.049),but no obvious linear relationship between HEV-IgM positive rate and age(t=2.034,P=2.034) and between-gender difference in HAV-IgM and HEV-IgM positive rates were observed(χ2=0.023,P=0.880;χ2=1.641,P=0.200).Conclusion The prevalence of HAV-IgM and HEV-IgM are high,with seasonal difference for HAV-IgM and positive correlation to age for HEV-IgM among employees of Guangzhou Baiyun International Airport.
Correlation between genetic polymorphism and susceptibility to childhood acute lymphoblastic leukemia
LI Hong-shan, WEN Xiao-mei, ZHENG Shi-hua.et al
2015, 31(7): 963-965. doi: 10.11847/zgggws2015-31-07-31
Abstract(841) HTML (214) PDF 939KB(86)
Abstract:
Objective To study the correlation between the polymorphism of glutathione S-transferase gene(GSTT1 present/null,GSTM1 present/null,and GSTP1 I105V)with the susceptibility to childhood acute lymphoblastic leukemia(ALL).Methods Totally 87 ALL patients and 120 healthy controls were enrolled.GSTT1 and GSTM1 genetic polymorphism was detected with multiple PCR and GSTP1 I 105V genetic polymorphism was detected with pyrosequencing.SPSS was employed in data analyses.Results Among the 207 samples from both the patients and the controls,the frequencies were 69.1% and 27.5% for GSTT1 wild and mutant genotype,30.9% and 72.5% for GSTM1 wild and mutant genotype,and 58%,33.8% and 8.2% for GSTP1 AA,AG and GG genotype.GSTT1 and GSTM1 null genotypes were not significantly associated with the risk of ALL(odds ratio[OR]=0.685,95% confidence interval[95%CI]:0.378-1.241 and OR=0.742,95%CI:0.396-1.390);GSTP1 GG genotype was associated with an increased ALL risk(OR=1.194,95%CI:0.645-2.150),while AG genotype was associated with a decreased ALL risk(OR=0.711,95%CI:0.237-1.820).Conclusion The genetic polymorphisms of GSTT1 present/null,GSTM1 present/null,and GSTP1 I105V are associated,but not significantly,with susceptibility to childhood acute lymphoblastic leukemia.
Relationship between negative life events and sleep quality among medical college students
GUO Li, ZHANG Ying, LI Xiao-liang.et al
2015, 31(7): 965-967. doi: 10.11847/zgggws2015-31-07-32
Abstract(1185) HTML (207) PDF 886KB(66)
Abstract:
Objective To examine the status of sleep quality and its association with negative life events among medical college students,and to provide evidences for improving sleeping quality of the students.Methods A self-administered questionnaire survey was conducted among 364 students selected from the Shenyang Medical College with stratified sampling.Adolescence Life Events Scale(ASLES)and Pittsburgh Sleep Quality Index(PSQI)questionnaire were used in the study.Results For all the students,20.6% had sleeping problems and the average PSQI score was 5.73 ± 2.46; the incidence of negative life events among the students ranged from 36.81%to 89.01% and the ALSEC score was 34.33± 13.98.The scores of ASLES and PSQI were positively correlated(r=0.270,P<0.001).Results of liner regression analysis showed that higher ASLES score predicted higher PSQI scores(t=5.530,P<0.001).The results of stepwise regression analysis showed that negative life events,such as study pressure,health adaptation,penalty factor,and other factors,could affect the quality of sleep(F=13.039,P=0.000).Conclusion There were a high prevalence of sleep disorders and a negative relationship between negative life events and the quality of sleep among the medical college students.
Prevalence of post-stroke depression among Chinese stroke patients:a meta-analysis
LI Ying, LI Guang-xiao
2015, 31(7): 968-972. doi: 10.11847/zgggws2015-31-07-33
Abstract(2399) HTML (297) PDF 986KB(243)
Abstract:
Objective To evaluate the prevalence of post-stroke depression(PSD)among Chinese stroke patients with meta-analysis and to provide references for clinical care of the patients.Methods Literatures search was performed using Chinese Biomedical Data-Base,China National Knowledge Infrastructure,WanFang Database,and VIP Chinese Science and Technology Periodical Database to retrieve studies focused on prevalence of PSD among patients with stroke from Janury 2000 through December 2014.Quality of the included studies was evaluated using Agency for Healthcare Research and Quality(AHRQ)scale.All statistical analysis was conducted with Comprehensive Meta Analysis(CMA)2.0 software.Results Totally 32 articles were included,with 15 834 stroke patients and 5 363 PSD patients involved.The overall prevalence of PSD among the stroke patients was 32.8%(95% confidence interval[95% CI]:29.5%-36.3%).Subgroup analysis showed that the prevalence of PSD for the patients with left hemisphere only stroke was significantly different from that of non-left hemisphere only stroke(41.7% vs.26.4%,Q=36.5;P<0.01).The prevalence of PSD was affected by the course of stroke,with the prevalence rates of 26.4%,37.6%,and 38.6% for the patients with the stroke within one month,1 to 6 months,and more than 6 months,respectively(Q=9.48,P<0.01).The PSD prevalence rate also varied when evaluated using different scales(Self-Rating Depression Scale[SDS].Hamilton Depression Scale[HAMD]:37.7% vs.30.0%,Q=4.96,P=0.03).No statistical differences were observed when the studies were stratified by sex,age,regions and subtype of stroke(with P>0.05).Conclusion The prevalence of PSD is high among Chinese stroke patients.Much attention should be paid to the mental health of stoke patients for improving quality of life of the patients.