Human exposure to bisphenol A and its health risks: a review
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Graphical Abstract
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Abstract
Human are exposed to bisphenol A (BPA) through various ways and dietary exposure is among one of them in general populations. The data on dietary exposure assessment indicated that the levels of human exposure to BPA are much lower than the tolerable daily intake (50μg/kg·bw/d) recommended by United States. Studies have revealed that BPA plays a weak estrogen-like role in human body resulting in endocrine disorder. For human health risks, BPA exposure was recognized to have impacts on levels of female sex hormone, functions of male reproductive system, and fetus growth and development and in addition to have relations with children obesity, recurrent abortion, polycystic ovary syndrome, and type 2 diabetes. BPA may lead to human health effects with a long-term low level exposure via various routes among general populations.
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