Advance Search
Volume 38 Issue 12
Dec.  2022
Turn off MathJax
Article Contents
WU Yong-jun, ZHANG Wei-sen, ZHOU Bai-jing, . Correlation between age at natural menopause and postmenopausal obesity: a population-based cross-sectional study in Guangzhou city[J]. Chinese Journal of Public Health, 2022, 38(12): 1544-1548. doi: 10.11847/zgggws1138576
Citation: WU Yong-jun, ZHANG Wei-sen, ZHOU Bai-jing, . Correlation between age at natural menopause and postmenopausal obesity: a population-based cross-sectional study in Guangzhou city[J]. Chinese Journal of Public Health, 2022, 38(12): 1544-1548. doi: 10.11847/zgggws1138576

Correlation between age at natural menopause and postmenopausal obesity: a population-based cross-sectional study in Guangzhou city

doi: 10.11847/zgggws1138576
  • Received Date: 2022-03-22
    Available Online: 2022-08-31
  • Publish Date: 2022-12-10
  •   Objective  To analyze the correlation between early or late age at natural menopause and obesity among postmenopausal women, and to provide reference for health care of postmenopausal women.   Methods  From November 2017 through January 2020, totally 5 646 natural menopausal women aged ≥ 50 years were recruited from the voluntary participants of a prospective cohort study on chronic diseases in middle-aged and elderly residents of Guangzhou city. The women's information on demographic characteristics and physical indicators (including body mass index [BMI], waist circumference [WC], and waist-hip ratio [WHR]) were collected from the baseline survey of the cohort study. Generalized linear model, multivariate logistic regression model and restricted cubic spline analysis model were adopted in data analysis using SPSS 25.0 and STATA 16.0.   Results  For all the women aged 60.0 ± 5.8 years, the mean age at menopause was 50.3 ± 3.1 years and the age at natural menopause was u-shaped associated with obesity. After adjusting for possible confounders, the results of multivariate logistic regression analysis showed that compared with the women with a normal age at natural menopause (46 – 53 years), the women with an early age at natural menopause (< 46) were more likely to have an increased risk of central obesity determined by WC (odds ratio [OR] = 1.32, 95% confidence interval [95% CI]: 1.03 – 1.69) or WHR (OR = 1.32, 95% CI: 1.06 – 1.64) and overweight/obesity determined by BMI (OR = 1.39, 95% CI: 1.13 – 1.71); while, the women with a late age at natural menopause (> 53) were also more likely to have an increased the risk of central obesity determined by WC ( OR = 1.34, 95% CI: 1.11 – 1.63) or WHR (OR = 1.41, 95% CI: 1.19 – 1.68) and overweight/obesity determined by BMI (OR = 1.49, 95% CI: 1.26 – 1.76).   Conclusion  Early or late age at natural menopause are associated with an increased risk of postmenopausal obesity for middle-aged and elderly women. The results suggest that the women with early or late age at natural menopause should pay more attention to muscle training and balanced diet and appropriately control the intake of food mainly providing energy.
  • loading
  • [1]
    Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980 – 2013: a systematic analysis for the Global Burden of Disease Study 2013[J]. The Lancet, 2014, 384(9945): 766 – 781. doi: 10.1016/S0140-6736(14)60460-8
    [2]
    宋孟娜, 程潇, 孔静霞, 等. 我国中老年人超重、肥胖变化情况及影响因素分析[J]. 中华疾病控制杂志, 2018, 22(8): 804 – 808. doi: 10.16462/j.cnki.zhjbkz.2018.08.010
    [3]
    钟晴, 李毅琳, 黄远霞, 等. 武汉市居民超重肥胖现状及影响因素分析[J]. 中国公共卫生, 2019, 35(9): 1210 – 1214. doi: 10.11847/zgggws1123568
    [4]
    卢露, 景翔, 王亚丽, 等. 山东省 ≥ 60岁老年人超重、肥胖和腹型肥胖流行现状及其影响因素分析[J]. 中国公共卫生, 2020, 36(4): 566 – 569. doi: 10.11847/zgggws1126075
    [5]
    王玥, 孟楠. 基于Joinpoint回归分析我国成人超重、肥胖流行趋势的性别差异[J]. 中国卫生统计, 2021, 38(4): 546 – 548.
    [6]
    曹志, 程杨杨, 李书, 等. 中老年人群中心性肥胖与多种慢性病的关联分析[J]. 中国慢性病预防与控制, 2019, 27(2): 81 – 84, 88. doi: 10.16386/j.cjpccd.issn.1004-6194.2019.02.001
    [7]
    陈路路, 苏健, 陶然, 等. 江苏省中老年居民中心性肥胖与慢性阻塞性肺疾病患病关系[J]. 中国公共卫生, 2021, 37(11): 1597 – 1601. doi: 10.11847/zgggws1132223
    [8]
    Shen LJ, Song LL, Liu BQ, et al. Effects of early age at natural menopause on coronary heart disease and stroke in Chinese women[J]. International Journal of Cardiology, 2017, 241: 6 – 11. doi: 10.1016/j.ijcard.2017.03.127
    [9]
    Shen L, Song L, Li H, et al. Association between earlier age at natural menopause and risk of diabetes in middle - aged and older Chinese women: the Dongfeng-Tongji Cohort Study[J]. Diabetes and Metabolism, 2017, 43(4): 345 – 350. doi: 10.1016/j.diabet.2016.12.011
    [10]
    Fu YL, Yu YQ, Wang SB, et al. Menopausal age and chronic diseases in elderly women: a cross - sectional study in northeast China[J]. International Journal of Environmental Research and Public Health, 2016, 13(10): 936. doi: 10.3390/ijerph13100936
    [11]
    Su HM, Jiang CQ, Zhang WS, et al. Natural menopausal age and cardiovascular disease risk factors in older Chinese women: Guangzhou Biobank Cohort Study[J]. Menopause, 2021, 28(12): 1410 – 1417. doi: 10.1097/GME.0000000000001856
    [12]
    Xu L, Lam TH, Jiang CQ, et al. Changes in adiposity in an older Chinese population in rapid economic transition[J]. Obesity (Silver Spring), 2016, 24(10): 2217 – 2223. doi: 10.1002/oby.21599
    [13]
    何权瀛, 高莹慧. 关于吸烟问题若干名词定义[J]. 中华结核和呼吸杂志, 2009, 32(1): 56. doi: 10.3760/cma.j.issn.1001-0939.2009.01.008
    [14]
    马冠生, 朱丹红, 胡小琪, 等. 中国居民饮酒行为现况[J]. 营养学报, 2005, 27(5): 362 – 365. doi: 10.3321/j.issn:0512-7955.2005.05.003
    [15]
    Deng HB, Macfarlane DJ, Thomas GN, et al. Reliability and validity of the IPAQ - Chinese: the Guangzhou Biobank Cohort Study[J]. Medicine and Science in Sports and Exercise, 2008, 40(2): 303 – 307. doi: 10.1249/mss.0b013e31815b0db5
    [16]
    Baek TH, Lim NK, Kim MJ, et al. Age at menarche and its association with dysglycemia in Korean middle - aged women[J]. Menopause, 2015, 22(5): 542 – 548. doi: 10.1097/GME.0000000000000353
    [17]
    Mishra GD, Chung HF, Cano A, et al. EMAS position statement: predictors of premature and early natural menopause[J]. Maturitas, 2019, 123: 82 – 88. doi: 10.1016/j.maturitas.2019.03.008
    [18]
    中华人民共和国国家卫生和计划生育委员会. 成人体重判定: WS/T 428 — 2013[S]. 北京: 中国质检出版社, 中国标准出版社, 2013.
    [19]
    吴坤. 营养与食品卫生学[M]. 5版. 北京: 人民卫生出版社, 2006: 184 – 185.
    [20]
    Lovejoy JC. The menopause and obesity[J]. Primary Care:Clinics in Office Practice, 2003, 30(2): 317 – 325. doi: 10.1016/S0095-4543(03)00012-5
    [21]
    Montazeri SA, Tehrani FR, Yarandi RB, et al. Effect of aging, menopause, and age at natural menopause on the trend in body mass index: a 15 - year population - based cohort[J]. Fertility and Sterility, 2019, 111(4): 780 – 786. doi: 10.1016/j.fertnstert.2018.12.017
    [22]
    Yang L, Li LM, Millwood IY, et al. Adiposity in relation to age at menarche and other reproductive factors among 300 000 Chinese women: findings from China Kadoorie Biobank study[J]. Inter-national Journal of Epidemiology, 2017, 46(2): 502 – 512.
    [23]
    Park CY, Lim JY, Park HY. Age at natural menopause in Koreans: secular trends and influences thereon[J]. Menopause, 2018, 25(4): 423 – 429. doi: 10.1097/GME.0000000000001019
    [24]
    Peters SAE, Huxley RR, Woodward M. Women′s reproductive health factors and body adiposity: findings from the UK Biobank[J]. International Journal of Obesity, 2016, 40(5): 803 – 808. doi: 10.1038/ijo.2015.254
    [25]
    Lizcano F, Guzman G. Estrogen deficiency and the origin of obesity during menopause[J]. BioMed Research International, 2014, 2014: 757461.
    [26]
    Zsakai A, Karkus Z, Utczas K, et al. Body fatness and endogenous sex hormones in the menopausal transition[J]. Maturitas, 2016, 87: 18 – 26. doi: 10.1016/j.maturitas.2016.02.006
    [27]
    Gupte AA, Pownall HJ, Hamilton DJ. Estrogen: an emerging regulator of insulin action and mitochondrial function[J]. Journal of Diabetes Research, 2015, 2015: 916585.
    [28]
    Wang M, Gong WW, Hu RY, et al. Age at natural menopause and associated factors in adult women: findings from the China Kadoorie Biobank study in Zhejiang rural area[J]. PLoS One, 2018, 13(4): e0195658. doi: 10.1371/journal.pone.0195658
    [29]
    韦晓淋, 华钰洁, 陆艳, 等. 月经初潮年龄对女性成年后近期和远期肥胖的影响[J]. 中华流行病学杂志, 2019, 40(2): 142 – 146. doi: 10.3760/cma.j.issn.0254-6450.2019.02.004
    [30]
    田恬, 罗涛, 陈珍, 等. 绝经女性初潮年龄与超重关联的研究[J]. 现代预防医学, 2020, 47(5): 830 – 834.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(3)

    Article views (356) PDF downloads(51) Cited by()
    Proportional views
    Publishing history
    • Receive:  2022-03-22
    • Online:  2022-08-31
    • Published:  2022-12-10

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return