A Study on Relationship between Carbon Disulfide and complaints and Signs of Nervous System in Workers

A cross-sectio nal study was carried in order to investigate the relat inonship between carbon disulfide(CS₂)and the complatints and signs of nerv ous system in rayon wor kers.326 subjects exposed to CS₂ in a viscose rayon factory as a exposure group,105 workers from the same factory,not exposed to CS₂ or to any other neurotoxic agent,served as referents.The average CS₂ exposures of the low-level study group is below 10mg/m³,and 31mg/m³ in high-level group.Non-conditional multiple logistic regression analysis was used to check for statistical differences in SAS sof-tware.During the analysis,age,sex,worktime,body mass index,smoking,drinking,schooling and marriage state was adjusted.The odds ratio has significantly increaased of some complaints in workers exposed to CS₂ at levels below the present threshold limit value (10mg/m³),as compared to controls.The dose-response relationship between the exopsure to carbon disulfide and the come;paints of nervous system was demonstrated.The pathological findings in clinical-neurological could not be detected except the sensitivity of temperature in person exposed to CS₂.The influence of low-level CS₂ on nervous sytem in workers could not be ingnored.